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| ファイル | 記述 | サイズ | フォーマット | |
|---|---|---|---|---|
| 21_0877.pdf | 735.13 kB | Adobe PDF | 見る/開く |
| タイトル: | PT-122Mの腎機能障害時における血中濃度の推移と血液生化学値に及ぼす影響 |
| その他のタイトル: | STUDIES ON PT122M : PLASMA CONCENTRATION IN IMPAIRED RENAL FUNCTION AND EFFECTS ON BLOOD CHEMICAL VALUES |
| 著者: | 加藤, 廣海  袴田, 隆義 浜野, 耕一郎 堀内, 英輔 多田, 茂 |
| 著者名の別形: | Kato, Hiromi Hakamada, Takayohi Hamano, Kohichiroh Horiuchi, Eisuke Tada, Shigeru |
| 発行日: | Oct-1975 |
| 出版者: | 京都大学医学部泌尿器科学教室 |
| 誌名: | 泌尿器科紀要 |
| 巻: | 21 |
| 号: | 9 |
| 開始ページ: | 877 |
| 終了ページ: | 891 |
| 抄録: | PT-122M (doxycycline hydrochloride) was administered intravenously to 4 subjects with normal renal function and 7 with moderately impaired and 11 with severely impaired. Plasma concentration and urinary excretion of the given antibiotic were investigated. Dosage was 200 mg on the first day and 100 mg per day for the following six days. No accumulation of the drug was observed in those who have some renal function left. Some accumulation was noted in those under hemodialysis because of no renal function. Blood chemical data remained stable despite administration of the drug. Only one case complained nausea which was relieved by slowing the speed of intravenous injection. No side effects were observed in others. |
| URI: | http://hdl.handle.net/2433/121874 |
| 出現コレクション: | Vol.21 No.9 |
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