99mTc-Sn-DMSA腎シンチグラフィーによる術前,術後の腎機能の評価

Abstract

It is a matter of fact that examination of renal function must be ideally such as able to show not only renal function itself but renal morphology. In the previous reports, we emphasized that 99mTc-Sn-dimercapto-succinic acid (DMSA) is an excellent renal imaging agent which accumulate in the renal cortex making a diagnostic renoscintigrams. Right to left ratio of renal uptake of DMSA was found to be well correlated with that of renal plasma flow estimated by 131I-Hippuran renograms (co-efficiency γ= 0.94). Therefore, the ratio of individual renal uptake of 99mTc-Sn-DMSA was regarded and applied as the ratio of individual renal cortical function. Forty-six cases had 99mTc-Sn-DMSA renoscintigraphy before and after urological surgery in order to evaluate their separate renal function. Of 46 cases, 6 cases were described precisely. 99mTc-DMSA renoscintigrams do not require collection of urine, are able to be performed even in obstructive uropathies and give us the information of separate kidney both functionally and morphologically. This examination will be useful to decide which of nephrectomy and reno-conservative surgery is adequate. It is also helpful as a follow-up method of postoperative recovery of renal function.