血液透析時に使用するヘパリンカルシウムとヘパリンナトリウムの比較検討

Abstract

Using heparin calcium (Ca) and heparin natrium (Na) as heparinization agent during hemodialysis, partial thromboplastin time, prothrombin time and thrombotest were measured before and at 2, 4, 6 hours after the start of hemodialysis in 13 cases. In 6 cases thrombotest was measured every 1 hour from immediately after the end of hemodialysis to 6 hours after the end of hemodialysis for comparison of length of time necessary for return to normal coagulation activity after hemodialysis between them. The results were as follows: 1) There was no significant difference between anticoagulation activity of heparin Ca and that of heparin Na during hemodialysis. 2) After hemodialysis, in 4 cases of 6 treated with heparin Ca coagulation activity returned to normal earlier than in the cases treated with heparin Na.