Pseudomonas cepaciaおよびPseudomonas aeruginosaによる慢性複雑性尿路感染症に対するDoxycyclineの効果について

Abstract

1) DOTC was administered to fourteen hospitalised patients with complicated urinary tract infection. Total dosage was 1 gram for 5 days. 2) Of fourteen patients, eleven were infected by Pseudomonas cepacia and three were by Pseudomonas aeruginosa. 3) Elimination of pathogens and improvement of urinary findings were obtained in 72.7% of the cases infected by Pseudomonas cepacia and in 66.6% of the cases infected by Pseudomonas aeruginosa, and the clinical effective rate was 71.4%. No particular side effect was observed. 4) The clinical effectiveness of DOTC will be well evaluated in complicated chronic urinary tract infection caused by P. cepacia and P. aeruginosa.