Calcified Bladder Cancerの1例 -膀胱癌の石灰化について-

Abstract

A 62-year-old man came to us with gross hematuria. KUB showed bilateral nephro- and ureterolithiasis as well as the round calcified shadow in the bladder area of walnut size with nodular and granular appearance. Drip infusion pyelography showed shadow defect in the bladder at the site of calcification. Cystoscopy verified tumor of the bladder. Partial cystectomy, ureteroneocystostomy on the right and bilateral ureterolithotomy were simultaneously performed. The tumor had pedicle with calcified necrotic surface. Its pathohistologic evaluation was Grade 1 and Stage A transitional cell carcinoma. The calcification of the bladder tumor on radiograph is rather rare and said to be 0.43 to 0.69% in incidence. Ferris reported exceptionally high percentage, 6.7%. In our clinic, this is the first case out of 167 bladder tumors. Therefore, the incidence is 0.6%. According to Hilbish's classification of the abnormal calcification of the soft tissues, our case belongs to dystrophic clacification. The pathogenesis of calcification of the necrotic tissue has been attributed to alkalinization of the tissue fluid due to CO2 output from the cells decreased respiration.