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dc.contributor.author | 川村, 研二 | ja |
dc.contributor.alternative | Kawamura, Kenji | en |
dc.date.accessioned | 2010-07-08T04:24:10Z | - |
dc.date.available | 2010-07-08T04:24:10Z | - |
dc.date.issued | 2010-06 | - |
dc.identifier.issn | 0018-1994 | - |
dc.identifier.uri | http://hdl.handle.net/2433/122352 | - |
dc.description.abstract | In 1941 Huggins and Hodges demonstrated that castration slowed progression of prostate cancer. Treatment with a luteinizing hormone releasing hormone (LHRH) agonist is a standard alternative to surgical castration for patients with prostate cancer and metastases. We evaluated patients with prostate cancer undergoing long-acting LH-RH agonist hormone therapy to determine the length of time that serum testosterone remains at castration level. Between June 2007 and October 2009, we studied 73 patients treated with LH-RH agonist. Castrate serum testosterone was defined at 50 ng/dl and less. The interval of administration of LH-RH agonist was extended to 5 months, and the testosterone level was measured. The testosterone level was 50 or less in almost all patients at 5 months after long-acting LH-RH therapy. The ratio of patients to whom dosing of LH-RH agonist was terminated who have a testosterone level of 50 ng/dl and lower wasat 100% to month 7 and 7% to months10 -19. We believe that therapy whereby longacting LH-RH agonist isdos ed may be extended to 5 to 7 monthsif male hormone valuesare monitored. Our data suggest that using serum testosterone to guide LH-RH hormone dosing is efficacious and costeffective. | en |
dc.format.mimetype | application/pdf | - |
dc.language.iso | jpn | - |
dc.publisher | 泌尿器科紀要刊行会 | ja |
dc.rights | 許諾条件により本文は2011-07-01に公開 | ja |
dc.subject | LH-RH agonists | en |
dc.subject | Testosterone | en |
dc.subject | Prostate cancer | en |
dc.subject.ndc | 494.9 | - |
dc.title | 血中テストステロンレベル測定は長期作用型LHRH アゴニストの投与間隔を延長できるか? | ja |
dc.title.alternative | Can Serum Testosterone Level Measurement Extend the Intervals of Administration of a Long-Acting LHRH Agonist ? | en |
dc.type | departmental bulletin paper | - |
dc.type.niitype | Departmental Bulletin Paper | - |
dc.identifier.ncid | AN00208315 | - |
dc.identifier.jtitle | 泌尿器科紀要 | ja |
dc.identifier.volume | 56 | - |
dc.identifier.issue | 6 | - |
dc.identifier.spage | 301 | - |
dc.identifier.epage | 304 | - |
dc.textversion | publisher | - |
dc.sortkey | 03 | - |
dc.address | 恵寿総合病院 | ja |
dc.startdate.bitstreamsavailable | 2011-07-01 | - |
dc.address.alternative | The Department of Urology, Keiju General Hospital | en |
dc.identifier.pmid | 20610920 | - |
dcterms.accessRights | open access | - |
dc.identifier.pissn | 0018-1994 | - |
dc.identifier.jtitle-alternative | Acta urologica Japonica | la |
dc.identifier.jtitle-alternative | Hinyokika Kiyo | en |
出現コレクション: | Vol.56 No.6 |
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