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ファイル | 記述 | サイズ | フォーマット | |
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25_0037.pdf | 292.52 kB | Adobe PDF | 見る/開く |
タイトル: | ACNU膀胱内注入療法 |
その他のタイトル: | ACNU BLADDER INSTILLATION THERAPY |
著者: | 荒木, 博孝 三品, 輝男 都田, 慶一 藤原, 光文 小林, 徳朗 渡辺, 泱 |
著者名の別形: | Araki, Hirotaka Mishina, Teruo Miyakoda, Keiichi Fujiwara, Terufumi Kobayashi, Tokuroh Watanabe, Hiroki |
発行日: | Jan-1979 |
出版者: | 京都大学医学部泌尿器科学教室 |
誌名: | 泌尿器科紀要 |
巻: | 25 |
号: | 1 |
開始ページ: | 37 |
終了ページ: | 41 |
抄録: | ACNU was instilled into the bladder of dogs and patients with bladder tumors. After the instillation, the concentration of ACNU in the serum, the bladder wall and the lymph nodes was measured. On the other hand, bladder instillation therapy with ACNU was performed in patients with bladder tumors, The results were as follows: 1) In dogs, the concentration of ACNU after the instillation was very low in the serum and was enough to inhibit tumor growth in the bladder wall and lymph nodes. 2) In patients with bladder tumor, the concentration of ACNU in the serum after the instillation was higher than that in dogs although the concentration in the bladder wall was similar to that in dogs. 3) In 7 patients with bladder tumor, ACNU bladder instillation therapy resulted in necrosis on the surface of tumors in 2 out of them. Slow but considerable bone marrow depression, however, was noticed in those two patients. 4) Accordingly, ACNU bladder instillation therapy should be done carefully with frequent checking on side effects. |
URI: | http://hdl.handle.net/2433/122371 |
出現コレクション: | Vol.25 No.1 |
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