前立腺の動脈造影に関する研究 第3編:動脈造影の血清フォスファターゼ値におよぼす影響

Abstract

1) Total serum acid phosphatase (TSAP), prostatic serum acid phosphatase (PSAP) and serum alkaline phosphatase (SALP) were measured before and after arteriographic study in 51 cases described in Part I and II. 2) Increase of TSAP level 10 minutes after pelvic arteriography was observe in 10% of non-prostatic diseases, in 23.8% of benign prostatic hypertrophy and in 35% of prostatic cancer cases. Increase in the former two conditions was interpreted as a false positive, whereas that in carcinoma of the prostate as a true response. 3) Marked increase of PSAP level 10 minutes after pelvic arteriography was noted in 50% of prostatic cancer cases but not in non-prostatic diseases and benign prostatic hypertrophy at all. 4) Increase of SALP level 10 minutes after pelvic arteriography was observed in 20% of prostatic cancer cases, but not in other two conditions. This increase was, however, interpreted as a false positive response. 5) In five cases of prostatic cancer under anti-androgen therapy, elevation of TSAP, PSAP or SALP could not be observed at all.