CONGENITAL MESOBLASTIC NEPHROMA: A CASE REPORT AND REVIEW OF LITERATURE

Abstract

乳児のongenital esoblastic nephromaは臨床的および病理組織学的な特徴でWilms腫瘍と別の疾患であると考えられるようになって10年以上たっている。しかしこの腫瘍はときにWilms腫瘍と混乱されるために不用意にも現在でもWilms腫瘍のような積極的な治療が行なわれる。れわれは本疾患の文献を考察し，英文および日本語の文献中の91例を解析した。その結果, 適切な術後療法をさけるために切除標本に対して迅速でかつ正確な病理組織学的診断の重要性を述べ，かつcongenital mesoblastic nephromaの特徴を記載した。

Congenital mesoblastic nephroma of infancy has been recognized for more than a decade as a different entity from the Wilms' tumor in its clinical and histopathological features. This tumor, however, is sometimes confused with Wilms' tumor and subsequently inadvertent and vigorous therapy compatible with that of Wilms' tumor is done even at present time. We reviewed the pertinent literature and analyzed 91 cases of congenital mesoblastic nephroma in English and Japanese literature. As a result we emphasized the importance of early and accurate histopathological diagnosis of the resected specimen to avoid inappropriate postoperative therapy and characterized the peculiar features of congenital mesoblastic nephroma in this paper.