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タイトル: | 膀胱腫瘍に対するCarboquone膀胱腔内注入療法の基礎的,臨床的検討 |
その他のタイトル: | FUNDAMENTAL AND CLINICAL STUDIES ON INTRA-VERICAL INFUSION OF CARBOQUONE FOR TREATMENT OF BLADDER TUMOR |
著者: | 小野, 浩 広本, 宣彦 中津, 博 碓井, 亜 藤井, 元広 相模, 浩二 畑地, 康助 鵜飼, 麟三 仁平, 寛巳 福重, 満 平山, 多秋 松木, 暁 梶尾, 克彦 白石, 恒雄 林, 睦雄 |
著者名の別形: | Ono, Hiroshi Hiromoto, Nobuhiko Nakatsu, Hiroshi Usui, Tsuguru Fujii, Motohiro Sagami, Kouji Hatachi, Kousuke Ukai, Rinzo Nihira, Hiromi Fukushige, Mitsuru Hirayama, Masaaki Matsuki, Satoru Kajio, Katsuhiko Shiraishi, Tsuneo Hayashi, Mutsuo |
発行日: | May-1980 |
出版者: | 京都大学医学部泌尿器科学教室 |
誌名: | 泌尿器科紀要 |
巻: | 26 |
号: | 5 |
開始ページ: | 619 |
終了ページ: | 627 |
抄録: | Carboquone preparations, Esquinone for injection and Esquinone injection, were infused into the bladder to investigate their antitumor activity and inactivation of carboquone in urine in 72 patients with superficial bladder tumors. The following conclusions were obtained: 1. Stability of carboquone was highly dependent on pH of the urine mixed with it. Its inactivation was marked at acidic pH. Reduction of the amount of urine during infusion and use of a larger amount of diluent are important to prevent the inactivation of carboquone. 2. Intra-vesical infusion of carboquone was evaluated to be effective in 51.4% patients. 3. No special difference in effectiveness was found between Esquinone for injection and Esquinone injection. 4. No difference in effectiveness was found between the patients with primary tumors and those with recurrent tumors. 5. As for side effects, Esquinone for injection and Esquinone injection caused irritant symptoms of the bladder in 36.4 and 52.0% of patients, respectively. 6. Carboquinone infused into the bladder had no influence on peripheral blood, liver function, and renal function. |
URI: | http://hdl.handle.net/2433/122637 |
出現コレクション: | Vol.26 No.5 |
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