Hemofiltrationの臨床的研究 第1報 : 溶質除去能

Abstract

Eight patients of renal insufficiency were treated by hemofiltration (HF) for about three months, and the removability of solute was investigated. In the HF treatment, filtration of 0.4 liters per unit body weight each was performed three times a week according to the post-dilution method. As the substitution fluid, the modified lactated Ringer's solution (Midorijuji) was used. The filtration of 0.4 liters provided sufficient removal of low molecular weight substance, and produced therapeutic effects similar to those of the conventional hemodialysis. The serum P and Ca dropped more significantly than in the hemodialysis method. Meanwhile, it was considered necessary to increase the content of Ca in the substitution fluid. No side effects assumed to be due to the substitution fluid; such as fever and hepatic function disorder, were recognized.