異形成腎および所属尿管の組織学的検討

Abstract

Clinicopathologic study of 12 dysplastic kidneys with special reference to ipsilateral ureters and contralateral kidneys was reported. (1) The clinical diagnoses were followings; VUR 1, posterior urethral valve 1, multicystic kidney 1, distal ureteral atresia 1, double ureter with ureteral atresia 1, ureteral ectopy 1, and ectopic ureterocele 6. (2) The presence of dysplastic elements such as primitive duct, metaplastic cartilage, cysts and nerve bundles were the histologic features of the kidneys. (3) The muscle bundles were hypoplastic in 4 ureters, hypertrophic in I, dysplastic in 2, normal in 2. One ureter with ectopic ureterocele was normal in the middle one third and dysplastic in the upper and lower portions. (4) Contralateral abnormalities were encountered in 8 cases. The finding of our study suggests that renal dysplasia is not a single malformation of metanephric tissues but rather the group of malformations of the whole urinary tract.