尿路結石症患者の血液,尿性状に対する猪苓湯の効果

Abstract

The analysis of the blood and the urine were performed in the 37 patients of urinary calculi (male 24; renal calculi 15, ureteral calculi 5, stone-negative 4, female 13; renal calculi 10, ureteral calculi 2, stone-negative 1), who visited our outpatient clinic from November 1979 to September 1980. The patients were administered "CHORE ITO" 5g per day, p.o. for over 3 months. The blood and the urine were taken in fasting condition in the morning over 3 months interval. Significant changes (p<0.05 by paired t test) were observed as followings. As to biochemical concentrations, increase in serum K, decrease in serum Ca, urine Na, K, Cl were observed as well as decrease in urine BUN and creatinine. As to liver function, increase in LDH and decrease in r-GTP were noted. Gas analysis showed increase in base excess. No significant change was observed in urine citrate, ionized Ca (Ca++) and % Ca++/Ca. The above results indicated that the drug had the effect of diuresis and potassium accumulation. Other possible effects of the drug, especially those on the urinary calculi were discussed.