小児睾丸腫瘍(embryonal cell carcinoma)の治療経験 (第2報)

Abstract

Cis-Diaminedichloroplatinum (Cis-platinum) was used for metastatic infantile embryonal cell carcinoma of the testis. A 3 year and 2 month old boy, who previously had received radical orchiectomy, chemotherapy and resection of the retroperitoneal metastatic tumor showed elevated a-fetoprotein level. Cis-platinum was given 15 to 20 mg/m2 daily for 5 days by one shot intravenous injection at 3-week intervals. An a-fetoprotein level decreased to normal range and was kept there for 2 months. The side effects were frequent vomitting, renal damage and mild myelosuppression. Cis-platinum is a promising agent in the treatment of advanced infantile testicular tumor.