前立腺肥大症および膀胱頚部硬化症に対するsulpirideの使用経験

Abstract

Sulpiride was orally used at a dose of 300 mg/day for the treatment of 18 cases of benign prostatic hyperplasia and 4 cases of bladder neck stenosis. The examinations were done before and after its administration about urinary difficulty, nocturia, feeling of incomplete emptying and residual urine volume and quantitative hormone analysis was performed in all cases about prolactin, testosterone, L.H. and F.S.H . The results were as follows; For benign prostatic hyperplasia, sulpiride was found effective in 13 of 18 cases, and for bladder neck stenosis it was effective in 2 of 4 cases within about 5 weeks administration. Hormonal quantitative analysis was done before and one week after the administration, and it was found that only prolactin was relative to sulpiride. No significant side effect was detected except for slight Parkinson's disease observed in one case of benign prostatic hyperplasia.