小児睾丸腫瘍の2例と本邦小児睾丸腫瘍249症例の統計的考察

Abstract

1)Two cases of testicular tumors in infants are presented. Case 1: N.H., a 9-month-old male infant, who had a left testicular tumor for 3 months, received left high orchiectomy. Histological diagnosis was an infantile type of embryonal carcinoma. Five months after operation, a retroperitoneal metastatic tumor was detected. The infant was treated with chemotherapy using actinomycin D (ACD) and vincristin (VCR), but this metastatic tumor began to enlarge again 3 months later. He died of cachexia 10 months after he had orchiectomy. Case 2: R. Y., an 8-month-old male infant with a right testicular tumor for 2 months had an astonishingly high (110, 517.9 ng/ml) serum AFP level, but his chest x-ray and his physical examination were normal. Right high orchiectomy was performed. Histological diagnosis was infantile type of embryonal carcinoma. After orchiectomy he was treated with chemotherapy using ACD and Co[60] irradiation for 3 months. He is alive and healthy 9 months after operation with no signs of recurrent disease. Case 3: A.T., a I-year-old boy with a left testiclliar tumor which was extirpated on October 16, 1961. The protocol he had received and the gross specimen of the tumor were later lost, but fortunately the microscopic specimen remained. Histological diagnosis was terato-yolk sac carcinoma. 2) The literature on 249 cases of testicular tumors in infants reported in Japan from 1968 to July 1980 is clinicostatistically analysed.