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dc.contributor.author今川, 章夫ja
dc.contributor.author玉置, 俊晃ja
dc.contributor.author米沢, 正隆ja
dc.contributor.author桑原, 守正ja
dc.contributor.author海部, 泰夫ja
dc.contributor.author逸見, 昭二ja
dc.contributor.alternativeImagawa, Akioen
dc.contributor.alternativeTamaki, Toshiakien
dc.contributor.alternativeYonezawa, Masatakaen
dc.contributor.alternativeKuwahara, Morimasaen
dc.contributor.alternativeKaifu, Yasuoen
dc.contributor.alternativeItsumi, Shojien
dc.date.accessioned2010-07-22T06:29:19Z-
dc.date.available2010-07-22T06:29:19Z-
dc.date.issued1982-04-
dc.identifier.issn0018-1994-
dc.identifier.urihttp://hdl.handle.net/2433/123072-
dc.description.abstractThe serum levels of Cefsulodin and Cefotiam, new semisynthetic cepharosporines, in uremic patients were determined during blood purification. Cefsulodin was given in a single intravenous dose of 0.5g to uremic patients before blood purification. Serum levels were 12.3-32.3 mcg/ml after 30 minutes, 7.2-17.6 mcg/ml after 2 hours and 3.4-8.9 mcg/ml after blood purification. The half-life of Cefsulodin during hemodialysis, hemodiafiltration and hemofiltration was 3.05 hours, 1.37 hours and 2.28 hours respectively. Cefotiam was given by the same method as Cefsulodin to uremic patients before blood purification. Serum levels were 23.2-49.7 mcg/ml after 30 minutes, 13.4-20.0 mcg/ml after 2 hours and 5.9-10.0 mcg/ml after blood purification. The half-life of Cefotiam during hemodialysis, hemodiafiltration and hemofiItration was 1.85 hours and 1.23 hours and 2.13 hours, respectively. These two new antibiotics were well dialysed or filtrated by .blood purification.en
dc.format.mimetypeapplication/pdf-
dc.language.isojpn-
dc.publisher京都大学医学部泌尿器科学教室ja
dc.publisher.alternativeDepartment of Urology, Faculty of Medicine, Kyoto Univeersityen
dc.subject.ndc494.9-
dc.titleCefsulodinおよびCefotiamの血液浄化療法時の血中濃度ja
dc.title.alternativeSERUM LEVELS OF CEFSULODIN AND CEFOTIAM DURING BLOOD PURIFICATION IN UREMIC PATIENTSen
dc.typedepartmental bulletin paper-
dc.type.niitypeDepartmental Bulletin Paper-
dc.identifier.ncidAN00208315-
dc.identifier.jtitle泌尿器科紀要ja
dc.identifier.volume28-
dc.identifier.issue4-
dc.identifier.spage391-
dc.identifier.epage395-
dc.textversionpublisher-
dc.sortkey05-
dc.address高松赤十字病院泌尿器科ja
dc.address海部医院ja
dc.address武田薬品工業株式会社中央研究所ja
dc.address.alternativethe Department of Urology, Takamatu Red Cross Hospitalen
dc.address.alternativeKaifu Clinicen
dc.address.alternativethe Central Research Division, Takeda Chemical Industries, Ltd.en
dcterms.accessRightsopen access-
dc.identifier.pissn0018-1994-
dc.identifier.jtitle-alternativeActa urologica Japonicala
dc.identifier.jtitle-alternativeHinyokika Kiyoen
出現コレクション:Vol.28 No.4

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