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タイトル: | TSAA-291(16β-Ethyl-17β-Hydroxy-4-Oestren-3-One)の中枢への影響 |
その他のタイトル: | EFFECT OF TSAA-291 (16P-ETHYL-17β-HYDROXY-4-OESTREN-3-ONE) ON THE HYPOTHALAMO-PITUITARY AXIS |
著者: | 島崎, 淳 宮内, 大成 |
著者名の別形: | Shimazaki, Jun Miyauchi, Taisei |
発行日: | Apr-1982 |
出版者: | 京都大学医学部泌尿器科学教室 |
誌名: | 泌尿器科紀要 |
巻: | 28 |
号: | 4 |
開始ページ: | 387 |
終了ページ: | 390 |
抄録: | Plasma hormone levels were determined before and after administration of TSAA-291 for 12 weeks and 1-2 months after final administration. The following results were obtained. 1) Gonadotropin levels showed a tendency to decline after administration and did not recover 1-2 months after final administration. The response of gonadotropins to LH-RH was more clearly suppressed. 2) Testosterone and 5a-dihydrotestosterone levels slightly decreased after drug administration and did not recover 1-2 months after final administration. 3) Cortisol level was not affected by TSAA-291. These results suggest that TSAA-291 has a slight suppressive effect on the hypothalamo-pituitary axis. |
URI: | http://hdl.handle.net/2433/123073 |
出現コレクション: | Vol.28 No.4 |
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