薬物性排尿障害の臨床研究

Abstract

Thirty-five patients with urinary retention caused by various medicines were seen during the last 2 years. They were 30 males and 5 females; 74% of them were over 60 years. The causative agents were anti-cholinergics, medications for the common cold, tranquilizers, narcotics and betaadrenergic blockers. Urinary retention developed faster in the patients who had taken anti-cholinergics or common cold remedies than in those who had taken tranquilizers or anti-depressants; they also recovered faster. Complications of colds and lower urinary tract obstruction were seen in 43% and 34% of the patients, respectively. Cystometry disclosed a stable bladder in only II out of 23 patients (48%). Treatment consisted of prompt cessation of the causative medicine, intermittent catheterization, and the administration of alpha-adrenergic blockers and parasympathomimetics.