腎細胞癌の臨床病理学的検討

Abstract

Clinicopathological studies were made of 95 cases (67 male and 28 female) of renal cell carcinoma in relation to prognosis. Nephrectomy was performed most frequently in the patients in their sixties. Possible relationships between the prognosis of the disease and each of the following items were examined: Five-year survival rate and stage of the carcinoma, and atypia of cell nuclei; i.e., grade, growth pattern, and cell type of the carcinoma. The results obtained revealed that the stage reflected the prognosis most distinctly. The five-year survival rate was 81 % for stages I and II, 0% for stage III, and 16% for stage IV. It was 100%, 21%, 12.5%, and 20% for grades 1, 2, 3, and 4, respectively. The five-year survival rate calculated according to growth pattern was 74% for the papillary pattern, 46.1 % for the tubular survival rate pattern, 62% for the cord pattern, and 24 % for the sheet pattern. The five-year survival rate calculated according to cell type was 54 % for the clear cell type, 49% for the granular cell type, and 32 % for the spindle cell type. In conclusion, the stage of renal cell carcinoma reflected prognosis most obviously. There was also a significant correlation between the prognosis of renal cell carcinoma and its grade, growth pattern, or cell type.