前立腺癌の臨床統計的観察

Abstract

Eighty-two patients with prostatic cancer first treated between 1967 and 1979 were followed and the following results were obtained. The incidence of prostatic cancer was 0.78% for the male outpatients and 6.3% for the male inpatients. The patients ranged from 42 to 88 years old with an average age of 71 years old. The most common complaints were urinary retention, dysuria, frequency and hematuria. About 80% of the chief complaints were related to urinary tract obstruction. Histological diagnosis was adenocarcinoma for all patients; 72 patients had well-differentiated adenocarcinoma and 10 had anaplastic cell carcinoma. At first examination about 43% of the patients were found to have elevated serum prostatic acid phosphatase and about 20% of the patients were found to have distant metastasis. Urinary cytologic examination was done on 40 patients: Positive findings were obtained in 42% of the cases of differentiated adenocarcinoma and 86% of the cases of anaplastic cell carcinoma. Four of the 82 cases were stage T0NxM0 cancer, 13 were stage T1- 2NxM0 cancer, 45 were stage T3-4NxM0 cancer and 20 were stage T0-4NXM0 cancer. The 5-year relative survival rate of all the patients was 84.1 % (S.E. 8%). The 5-year relative survival rate .of the patients with stage T3-4NxM0 cancer (87.4%, S.E. 16%) was better than that of the patients with stage T0-4NxM1 cancer (57.2%, S.E. 16%), the difference being statistically significant.