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j.rmedc.2009.05.006.pdf | 199.61 kB | Adobe PDF | 見る/開く |
タイトル: | Successful treatment with carboplatin and etoposide in a small-cell lung cancer patient undergoing hemodialysis |
著者: | Kim, Young Hak Mio, Tadashi Hamamoto, Yumi Mishima, Michiaki |
著者名の別形: | 金, 永学 |
キーワード: | Small-cell lung cancer Hemodialysis Chemotherapy Pharmacokinetic analysis |
発行日: | 2010 |
出版者: | Elsevier Ltd |
誌名: | Respiratory Medicine CME |
巻: | 3 |
号: | 2 |
開始ページ: | 68 |
終了ページ: | 70 |
抄録: | Chemotherapy for cancer patients with chronic renal failure, undergoing hemodialysis (HD), has not been well established. A 78-year-old woman with chronic renal failure due to hypertensive nephropathy, undergoing HD, was diagnosed with small-cell lung cancer (SCLC) with multiple-organ metastases. She was treated with 4 cycles of carboplatin (CBDCA) and etoposide (ETP) chemotherapy and a partial response was achieved. She remained progression-free for at least 12 months after the completion of chemotherapy. Pharmacokinetic analysis (PK) revealed that both agents were rapidly eliminated by HD; however, the remnant platinum remained longer in the plasma. Chemotherapy with CBDCA and ETP was effective and could be safely administered to a patient with SCLC undergoing HD. |
著作権等: | © 2010 Elsevier Ltd この論文は出版社版でありません。引用の際には出版社版をご確認ご利用ください。 This is not the published version. Please cite only the published version. |
URI: | http://hdl.handle.net/2433/126736 |
DOI(出版社版): | 10.1016/j.rmedc.2009.05.006 |
出現コレクション: | 学術雑誌掲載論文等 |
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