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タイトル: | 前立腺肥大症に対するナフトピジルとタムスロシンの臨床効果の比較 |
その他のタイトル: | A Randomized Controlled Study Comparing Clinical Effects of Naftopidil and Tamsulosin on Benign Prostatic Hyperplasia |
著者: | 羽入, 修吾 波田野, 彰彦 西山, 勉 小原, 健司 高橋, 公太 |
著者名の別形: | Hanyu, Shugo Hatano, Akihiko Nishiyama, Tsutomu Obara, Kenji Takahashi, Kohta |
キーワード: | Benign prostatic hyperplasia Naftopidil Tamsulosin |
発行日: | Sep-2010 |
出版者: | 泌尿器科紀要刊行会 |
誌名: | 泌尿器科紀要 |
巻: | 56 |
号: | 9 |
開始ページ: | 489 |
終了ページ: | 494 |
抄録: | A prospective randomized controlled study was performed to compare the clinical effects of naftopidil and tamsulosin. Men complaining of lower urinary tract symptoms due to benign prostatic hyperplasia were randomized into two groups : one receiving 50mg naftopidil once daily (Naf group, n=36 patients), and the other receiving 0.2 mg tamsulosin once daily (Tam group, n=32 patients). In the Naf group at 12 weeks, 7 items of the International Prostate Symptom Score (IPSS), storage and voiding symptoms, total IPSS, quality of life (QOL) index (QOLI) and Qmax were improved significantly. In the Tam group at 12 weeks, 6 items of IPSS except urgency, storage and voiding symptoms, total IPSS, QOLI and Qmax were improved significantly. Improvement of residual urine volume (PVR) was insignificant in both groups. In intergroup comparison between the Naf and the Tam groups, variations of 7 items of IPSS, storage and voiding symptoms, total IPSS, QOLI, Qmax and PVR at 4 and 12 weeks after treatment were not statistically significant. There was almost no difference in clinical efficacy between Naf and Tam. |
著作権等: | 許諾条件により本文は2011-10-01に公開 |
URI: | http://hdl.handle.net/2433/126851 |
PubMed ID: | 20940522 |
出現コレクション: | Vol.56 No.9 |
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