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タイトル: Age-related changes in the trachea in healthy adults.
著者: Sakai, Hiroaki
Nakano, Yasutaka
Muro, Shigeo  KAKEN_id
Hirai, Toyohiro  KAKEN_id
Takubo, Yasutaka
Oku, Yoshitaka
Hamakawa, Hiroshi
Takahashi, Ayuko
Sato, Toshihiko
Chen, Fengshi
Sahara, Hisashi
Fujinaga, Takuji
Sato, Kiyoshi
Sonobe, Makoto
Shoji, Tsuyoshi
Miyahara, Ryo
Okubo, Kenichi
Bando, Toru
Hirata, Toshiki
Date, Hiroshi  kyouindb  KAKEN_id
Mishima, Michiaki
著者名の別形: 阪井, 宏彰
発行日: 2010
出版者: Kluwer/Springer
誌名: Advances in experimental medicine and biology
巻: 662
号: Part 1
開始ページ: 115
終了ページ: 120
抄録: To investigate age-related changes in the shape of trachea, normal male volunteers (n = 83, mean +/- SD: 47.7 +/- 20.2 years old) underwent inspiratory CT scans at full inspiration and lung function tests. Subjects who showed VC < 80% predicted or FEV1 < 80% predicted on lung function tests were excluded. The CT data, which is located at 2.0 cm above the aortic arch, were transferred to a personal computer. The tracheal area (St) and two parameters, Tracheal index (Ti) and Circularity (Ci) indicating the shape of the trachea, were automatically calculated. Ti was defined the ratio of the coronal to the sagittal diameter of the trachea, and the Ci (Ci = 4piS/L2, S: tracheal area, L: tracheal perimeter) was used to indicate the roundness of the trachea. A Ci value of less than 1 indicated the distortion of the roundness. Both St and St/BSA (body surface area) showed a significant correlation with age (r = 0.37, r = 0.52; p = 0.0006, p < 0.0001). Ti was not correlated with age (r = -0.20; p = 0.0697), whereas Ci was significantly correlated with age (r = -0.32; p = 0.00364). There were measurable age related changes of the trachea both in the area and the shape. Aging results in the increased tracheal area and a distortion of the roundness.
著作権等: The original publication is available at www.springerlink.com
This is not the published version. Please cite only the published version.
この論文は出版社版でありません。引用の際には出版社版をご確認ご利用ください。
URI: http://hdl.handle.net/2433/128869
DOI(出版社版): 10.1007/978-1-4419-1241-1_16
PubMed ID: 20204780
出現コレクション:学術雑誌掲載論文等

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