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dc.contributor.author酒井, 英樹ja
dc.contributor.author井川, 掌ja
dc.contributor.author大仁田, 亨ja
dc.contributor.author古川, 正隆ja
dc.contributor.author計屋, 知彰ja
dc.contributor.author林, 幹男ja
dc.contributor.author松屋, 福蔵ja
dc.contributor.author志田, 洋平ja
dc.contributor.author西村, 直樹ja
dc.contributor.author与儀, 安男ja
dc.contributor.author鶴崎, 俊文ja
dc.contributor.author竹原, 浩介ja
dc.contributor.author野俣, 浩一郎ja
dc.contributor.author白石, 和孝ja
dc.contributor.author正野, 武文ja
dc.contributor.author青木, 大勇ja
dc.contributor.author金武, 洋ja
dc.contributor.alternativeSakai, Hidekien
dc.contributor.alternativeIgawa, Tsukasaen
dc.contributor.alternativeOnita, Toruen
dc.contributor.alternativeFurukawa, Masatakaen
dc.contributor.alternativeHakariya, Tomoakien
dc.contributor.alternativeHayashi, Mikioen
dc.contributor.alternativeMatsuya, Fukuzoen
dc.contributor.alternativeShida, Yoheien
dc.contributor.alternativeNishimura, Naokien
dc.contributor.alternativeYogi, Yasuoen
dc.contributor.alternativeTsurusaki, Toshifumien
dc.contributor.alternativeTakehara, Kousukeen
dc.contributor.alternativeNomata, Koichiroen
dc.contributor.alternativeShiraishi, Kazutakaen
dc.contributor.alternativeShono, Takefumien
dc.contributor.alternativeAoki, Daiyuen
dc.contributor.alternativeKanetake, Hiroshien
dc.date.accessioned2011-02-09T02:24:55Z-
dc.date.available2011-02-09T02:24:55Z-
dc.date.issued2011-01-
dc.identifier.issn0018-1994-
dc.identifier.urihttp://hdl.handle.net/2433/135441-
dc.description.abstractA total of 100 patients with benign prostatic hyperplasia (BPH) and overactive bladder (OAB) symptoms (BPH/OAB), enrolled between June 2006 to March 2008, were randomly divided into 2 groups of morning medication (M) and evening medication (E) groups, then 50 mg of naftopidil was given once a day after breakfast or supper for 8 weeks. Data were available for efficacy analysis on 80 patients (M group ; 43, E group ; 37). Naftopidil significantly improved the overall international prostatic symptom score ; from 19.2±7.9 to 11.7±5.8 in the M group and from 19.4±6.4 to 12.3±6.8 in the E group (p<0.0001), QOL score from 4.9±0.8 to 3.2±1.4 in the M group and from 5.0±0.8 to 3.6±1.3 in the E group (p<0.0001), and OAB symptom score from 7.8±2.6 to 5.0±2.5 in the M group (p<0.0001) and from 8.6±2.9 to 5.8± 3.3 in the E group (p<0.0001). There was no significant difference in the incidence of adverse effects betwen the M group (6.1%) and E group (2.2%). These results suggest that naftopidil improves storage symptoms as well as voiding symptoms regardless of timing of administration.en
dc.format.mimetypeapplication/pdf-
dc.language.isojpn-
dc.publisher泌尿器科紀要刊行会ja
dc.rights許諾条件により本文は2012-02-01に公開ja
dc.subjectBenign prostatic hyperplasiaen
dc.subjectOveractive bladderen
dc.subjectNaftopidilen
dc.subjectTiming of administrationen
dc.subject.ndc494.9-
dc.title過活動膀胱症状を有する前立腺肥大症に対するナフトピジルの有効性の検討 : 朝投与と夕投与の前向き無作為化比較試験ja
dc.title.alternativeEfficacy of Naftopidil in Patients with Overactive Bladder Associated with Benign Prostatic Hyperplasia: Prospective Randomized Controlled Study to Compare Differences in Efficacy Between Morning and Evening Medicationen
dc.typedepartmental bulletin paper-
dc.type.niitypeDepartmental Bulletin Paper-
dc.identifier.ncidAN00208315-
dc.identifier.jtitle泌尿器科紀要ja
dc.identifier.volume57-
dc.identifier.issue1-
dc.identifier.spage7-
dc.identifier.epage13-
dc.textversionpublisher-
dc.sortkey02-
dc.address長崎大学大学院医歯薬学総合研究科腎泌尿器病態学ja
dc.address長崎大学大学院医歯薬学総合研究科腎泌尿器病態学ja
dc.address長崎大学大学院医歯薬学総合研究科腎泌尿器病態学ja
dc.address佐世保市立総合病院泌尿器科ja
dc.address佐世保市立総合病院泌尿器科ja
dc.address国立病院機構長崎医療センター泌尿器科ja
dc.address国立病院機構長崎医療センター泌尿器科ja
dc.address国立病院機構長崎医療センター泌尿器科ja
dc.address健康保険諫早総合病院泌尿器科ja
dc.address健康保険諫早総合病院泌尿器科ja
dc.address長崎県島原病院泌尿器科ja
dc.address長崎県島原病院泌尿器科ja
dc.address長崎市立市民病院泌尿器科ja
dc.address聖フランシスコ病院泌尿器科ja
dc.address五島中央病院泌尿器科ja
dc.address五島中央病院泌尿器科ja
dc.address長崎大学大学院医歯薬学総合研究科腎泌尿器病態学ja
dc.startdate.bitstreamsavailable2012-02-01-
dc.address.alternativeThe Department of Nephro-Urology, Nagasaki University Graduate School of Biomedical Sciencesen
dc.address.alternativeThe Department of Nephro-Urology, Nagasaki University Graduate School of Biomedical Sciencesen
dc.address.alternativeThe Department of Nephro-Urology, Nagasaki University Graduate School of Biomedical Sciencesen
dc.address.alternativeThe Department of Urology, Sasebo General Hospitalen
dc.address.alternativeThe Department of Urology, Nagasaki Medical Centeren
dc.address.alternativeThe Department of Urology, Nagasaki Medical Centeren
dc.address.alternativeThe Department of Urology, Isahaya General Hospitalen
dc.address.alternativeThe Department of Urology, Isahaya General Hospitalen
dc.address.alternativeThe Department of Urology, Nagasaki Prefecture Shimabara Hospitalen
dc.address.alternativeThe Department of Urology, Nagasaki Prefecture Shimabara Hospitalen
dc.address.alternativeThe Department of Urology, Nagasaki Municipal Hospitalen
dc.address.alternativeThe Department of Urology, St Francis Hospitalen
dc.address.alternativeThe Department of Urology, Goto Chuoh Hospitalen
dc.address.alternativeThe Department of Urology, Goto Chuoh Hospitalen
dc.address.alternativeThe Department of Nephro-Urology, Nagasaki University Graduate School of Biomedical Sciencesen
dc.identifier.pmid21304253-
dcterms.accessRightsopen access-
dc.identifier.pissn0018-1994-
dc.identifier.jtitle-alternativeActa urologica Japonicala
dc.identifier.jtitle-alternativeHinyokika Kiyoen
出現コレクション:Vol.57 No.1

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