Three-tiered risk stratification model to predict progression in Barrett's esophagus using epigenetic and clinical features.

Sato, Fumiaki; Jin, Zhe; Schulmann, Karsten; Wang, Jean; Greenwald, Bruce D; Ito, Tetsuo; Kan, Takatsugu; Hamilton, James P; Yang, Jian; Paun, Bogdan; David, Stefan; Olaru, Alexandru; Cheng, Yulan; Mori, Yuriko; Abraham, John M; Yfantis, Harris G; Wu, Tsung-Teh; Fredericksen, Mary B; Wang, Kenneth K; Canto, Marcia; Romero, Yvonne; Feng, Ziding; Meltzer, Stephen J

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http://hdl.handle.net/2433/138086

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DCフィールド	値	言語
dc.contributor.author	Sato, Fumiaki	en
dc.contributor.author	Jin, Zhe	en
dc.contributor.author	Schulmann, Karsten	en
dc.contributor.author	Wang, Jean	en
dc.contributor.author	Greenwald, Bruce D	en
dc.contributor.author	Ito, Tetsuo	en
dc.contributor.author	Kan, Takatsugu	en
dc.contributor.author	Hamilton, James P	en
dc.contributor.author	Yang, Jian	en
dc.contributor.author	Paun, Bogdan	en
dc.contributor.author	David, Stefan	en
dc.contributor.author	Olaru, Alexandru	en
dc.contributor.author	Cheng, Yulan	en
dc.contributor.author	Mori, Yuriko	en
dc.contributor.author	Abraham, John M	en
dc.contributor.author	Yfantis, Harris G	en
dc.contributor.author	Wu, Tsung-Teh	en
dc.contributor.author	Fredericksen, Mary B	en
dc.contributor.author	Wang, Kenneth K	en
dc.contributor.author	Canto, Marcia	en
dc.contributor.author	Romero, Yvonne	en
dc.contributor.author	Feng, Ziding	en
dc.contributor.author	Meltzer, Stephen J	en
dc.contributor.alternative	佐藤, 史顕	ja
dc.date.accessioned	2011-03-04T05:41:24Z	-
dc.date.available	2011-03-04T05:41:24Z	-
dc.date.issued	2008-04	-
dc.identifier.issn	1932-6203	-
dc.identifier.uri	http://hdl.handle.net/2433/138086	-
dc.description.abstract	Barrett's esophagus predisposes to esophageal adenocarcinoma. However, the value of endoscopic surveillance in Barrett's esophagus has been debated because of the low incidence of esophageal adenocarcinoma in Barrett's esophagus. Moreover, high inter-observer and sampling-dependent variation in the histologic staging of dysplasia make clinical risk assessment problematic. In this study, we developed a 3-tiered risk stratification strategy, based on systematically selected epigenetic and clinical parameters, to improve Barrett's esophagus surveillance efficiency.	en
dc.format.mimetype	application/pdf	-
dc.language.iso	eng	-
dc.publisher	Public Library of Science(PLoS)	en
dc.rights	© 2008 Sato et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.	en
dc.subject.mesh	Barrett Esophagus/diagnosis	en
dc.subject.mesh	Barrett Esophagus/pathology	en
dc.subject.mesh	Cell Differentiation	en
dc.subject.mesh	Disease Progression	en
dc.subject.mesh	Disease-Free Survival	en
dc.subject.mesh	Endoscopy/methods	en
dc.subject.mesh	Epigenesis, Genetic	en
dc.subject.mesh	Esophageal Neoplasms/diagnosis	en
dc.subject.mesh	Humans	en
dc.subject.mesh	Methylation	en
dc.subject.mesh	Precancerous Conditions	en
dc.subject.mesh	ROC Curve	en
dc.subject.mesh	Reproducibility of Results	en
dc.subject.mesh	Risk	en
dc.subject.mesh	Risk Assessment/methods	en
dc.subject.mesh	Treatment Outcome	en
dc.title	Three-tiered risk stratification model to predict progression in Barrett's esophagus using epigenetic and clinical features.	en
dc.type	journal article	-
dc.type.niitype	Journal Article	-
dc.identifier.jtitle	PloS one	en
dc.identifier.volume	3	-
dc.identifier.issue	4	-
dc.relation.doi	10.1371/journal.pone.0001890	-
dc.textversion	publisher	-
dc.identifier.artnum	e1890	-
dc.identifier.pmid	18382671	-
dcterms.accessRights	open access	-
出現コレクション:	学術雑誌掲載論文等

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