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| ファイル | 記述 | サイズ | フォーマット | |
|---|---|---|---|---|
| journal.pone.0019799.pdf | 527.4 kB | Adobe PDF | 見る/開く |
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| DCフィールド | 値 | 言語 |
|---|---|---|
| dc.contributor.author | Onomoto, Koji | en |
| dc.contributor.author | Morimoto, Shiho | en |
| dc.contributor.author | Kawaguchi, Takahisa | en |
| dc.contributor.author | Toyoda, Hidenori | en |
| dc.contributor.author | Tanaka, Masami | en |
| dc.contributor.author | Kuroda, Masahiko | en |
| dc.contributor.author | Uno, Kazuko | en |
| dc.contributor.author | Kumada, Takashi | en |
| dc.contributor.author | Matsuda, Fumihiko | en |
| dc.contributor.author | Shimotohno, Kunitada | en |
| dc.contributor.author | Fujita, Takashi | en |
| dc.contributor.author | Murakami, Yoshiki | en |
| dc.contributor.alternative | 村上, 善基 | ja |
| dc.date.accessioned | 2011-06-07T00:33:56Z | - |
| dc.date.available | 2011-06-07T00:33:56Z | - |
| dc.date.issued | 2011 | - |
| dc.identifier.issn | 1932-6203 | - |
| dc.identifier.uri | http://hdl.handle.net/2433/141816 | - |
| dc.description.abstract | Despite being expensive, the standard combination of pegylated interferon (Peg-IFN)- α and ribavirin used to treat chronic hepatitis C (CH) results in a moderate clearance rate and a plethora of side effects. This makes it necessary to predict patient outcome so as to improve the accuracy of treatment. Although the antiviral mechanism of genetically altered IL28B is unknown, IL28B polymorphism is considered a good predictor of IFN combination treatment outcome. | en |
| dc.format.mimetype | application/pdf | - |
| dc.language.iso | eng | - |
| dc.publisher | Public Library of Science | en |
| dc.rights | © 2011 Onomoto et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. | en |
| dc.title | Dysregulation of IFN system can lead to poor response to pegylated interferon and ribavirin therapy in chronic hepatitis C. | en |
| dc.type | journal article | - |
| dc.type.niitype | Journal Article | - |
| dc.identifier.jtitle | PloS one | en |
| dc.identifier.volume | 6 | - |
| dc.identifier.issue | 5 | - |
| dc.relation.doi | 10.1371/journal.pone.0019799 | - |
| dc.textversion | publisher | - |
| dc.identifier.artnum | e19799 | - |
| dc.identifier.pmid | 21603632 | - |
| dcterms.accessRights | open access | - |
| 出現コレクション: | 学術雑誌掲載論文等 | |
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