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Title: 術前化学療法が有効であった成人型Wilms' tumor の1例
Other Titles: Successful Treatment of a Case of Advanced Adult Wilms' Tumor with Pre-Surgical Chemotherapy, Irradiationan and Radical Nephrectomy
Authors: 山岸, 敦史  KAKEN_name
櫻井, 俊彦  KAKEN_name
内藤, 整  KAKEN_name
槻木, 真明  KAKEN_name
加藤, 智幸  KAKEN_name
長岡, 明  KAKEN_name
冨田, 善彦  KAKEN_name
岩場, 晶子  KAKEN_name
山川, 光徳  KAKEN_name
Author's alias: Yamagishi, Atsushi
Sakurai, Toshihiko
Naito, Sei
Tsukigi, Masaaki
Kato, Tomoyuki
Nagaoka, Akira
Tomita, Yoshihiko
Iwaba, Akiko
Yamakawa, Mitsunori
Keywords: Adult Wilms' tumor
Neoadjuvant chemotherapy
Issue Date: Apr-2011
Publisher: 泌尿器科紀要刊行会
Journal title: 泌尿器科紀要
Volume: 57
Issue: 4
Start page: 189
End page: 192
Abstract: A 37-year-old male was referred with a huge renal mass and multiple lung lesions. Abdominal and chest computed tomographic scan revealed a 11×15×17. 5 cm right renal tumor and multiple lung metastases. Neither tumor was enhanced, and no lymph adenopathy was detected. Percutaneous needle core biopsy was performed and the tumors were diagnosed as Wilms’ tumor histologically supported by immunohistological positive staining to WT-1 and CD56. Since lung metastases were detected and the renal tumor reached the abdominal aorta on the left side, presurgical systemic chemotherapy (ifosphamide+ carboplatin+etoposide ; ICEx 4 courses) was performed. The renal tumor and the lung metastases were markedly decreased in size and subjected to a radical nephrectomy. Histological examination confirmed the diagnosis of Wilms’ tumor without anaplastic change categorized as mesenchymal type. As an adjuvant therapy, irradiation to renal bed (40 Gy/20 fr) and bilateral lung (12 Gy/8 fr) were performed. Six months after the end of the therapy, no evidence of recurrence was detected.
Rights: 許諾条件により本文は2012-05-01に公開
PubMed ID: 21646849
Appears in Collections:Vol.57 No.4

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