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Title: 原発性マクログロブリン血症による尿管アミロイドーシスの1例
Other Titles: A Case of Amyloidosis of the Ureter Caused by Primary Macroglobulinemia
Authors: 宮﨑, 有  KAKEN_name
神波, 大己  KAKEN_name
清水, 洋祐  KAKEN_name
井上, 貴博  KAKEN_name
大久保, 和俊  KAKEN_name
渡部, 淳  KAKEN_name
吉村, 耕治  KAKEN_name
兼松, 明弘  KAKEN_name
西山, 博之  KAKEN_name
小川, 修  KAKEN_name
Author's alias: Miyazaki, Yu
Kamba, Tomomi
Shimizu, Yosuke
Inoue, Takahiro
Okubo, Kazutoshi
Watanabe, Jun
Yoshimura, Koji
Kanematsu, Akihiro
Nishiyama, Hiroyuki
Ogawa, Osamu
Keywords: AL amyloidosis
primary macroglobulinemia
Issue Date: Apr-2011
Publisher: 泌尿器科紀要刊行会
Journal title: 泌尿器科紀要
Volume: 57
Issue: 4
Start page: 185
End page: 188
Abstract: A 78-year-old woman was referred to our hospital with chief complaint of colicky right flank pain. Computed tomography (CT) demonstrated right hydronephrosis and a wall thickening in the right ureteropelvic junction. Right nephroureterectomy was performed under a clinical diagnosis of invasive ureteral cancer. Histological examination revealed immunoglobulin light chain (AL) amyloidosis of the ureter. Although amyloid deposition seemed to be localized to the ureter alone, bone marrow biopsy revealed primary macroglobulinemia. After 23 months, no signs or symptoms suggesting the progression of amyloidosis or macroglobulinemia have been pointed out. AL amyloidosis arising secondarily to plasma cell disorder is called immunocytic amyloidosis. In general, immunocytic amyloidosis accompanies deposition of the amyloid protein to various organs of the whole body, and causes multiple clinical symptoms related to amyloid deposition. Even though the clinical manifestation indicates the localized disease like the presented case, close examination of immunocytic amyloidosis is important.
Rights: 許諾条件により本文は2012-05-01に公開
PubMed ID: 21646848
Appears in Collections:Vol.57 No.4

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