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Title: Differential prefrontal white matter development in chimpanzees and humans.
Authors: Sakai, Tomoko
Mikami, Akichika
Tomonaga, Masaki  kyouindb  KAKEN_id  orcid https://orcid.org/0000-0002-9319-6991 (unconfirmed)
Matsui, Mie
Suzuki, Juri  kyouindb  KAKEN_id
Hamada, Yuzuru  kyouindb  KAKEN_id
Tanaka, Masayuki
Miyabe-Nishiwaki, Takako  kyouindb  KAKEN_id
Makishima, Haruyuki
Nakatsukasa, Masato  kyouindb  KAKEN_id
Matsuzawa, Tetsuro  kyouindb  KAKEN_id
Author's alias: 酒井, 朋子
松沢, 哲郎
Issue Date: 23-Aug-2011
Publisher: Elsevier Ltd.
Journal title: Current biology : CB
Volume: 21
Issue: 16
Start page: 1397
End page: 1402
Abstract: A comparison of developmental patterns of white matter (WM) within the prefrontal region between humans and nonhuman primates is key to understanding human brain evolution. WM mediates complex cognitive processes and has reciprocal connections with posterior processing regions [1, 2]. Although the developmental pattern of prefrontal WM in macaques differs markedly from that in humans [3], this has not been explored in our closest evolutionary relative, the chimpanzee. The present longitudinal study of magnetic resonance imaging scans demonstrated that the prefrontal WM volume in chimpanzees was immature and had not reached the adult value during prepuberty, as observed in humans but not in macaques. However, the rate of prefrontal WM volume increase during infancy was slower in chimpanzees than in humans. These results suggest that a less mature and more protracted elaboration of neuronal connections in the prefrontal portion of the developing brain existed in the last common ancestor of chimpanzees and humans, and that this served to enhance the impact of postnatal experiences on neuronal connectivity. Furthermore, the rapid development of the human prefrontal WM during infancy may help the development of complex social interactions, as well as the acquisition of experience-dependent knowledge and skills to shape neuronal connectivity.
Rights: © 2011 Elsevier Ltd.
この論文は著者最終稿です。内容が印刷版と異なることがありますので、引用の際には出版社版をご確認ご利用ください。This is the Accepted Author Manuscript. Please cite only the published version.
URI: http://hdl.handle.net/2433/147262
DOI(Published Version): 10.1016/j.cub.2011.07.019
PubMed ID: 21835623
Appears in Collections:Journal Articles

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