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j.jchromb.2011.04.033.pdf828.53 kBAdobe PDF見る/開く
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dc.contributor.authorOmori, Taketoen
dc.contributor.authorHonda, Aien
dc.contributor.authorMihara, Hisaakien
dc.contributor.authorKurihara, Tatsuoen
dc.contributor.authorEsaki, Nobuyoshien
dc.contributor.alternative三原, 久明ja
dc.contributor.alternative栗原, 達夫ja
dc.contributor.alternative江崎, 信芳ja
dc.date.accessioned2011-12-21T07:56:15Z-
dc.date.available2011-12-21T07:56:15Z-
dc.date.issued2011-11-01-
dc.identifier.issn1873-376X-
dc.identifier.urihttp://hdl.handle.net/2433/151862-
dc.description.abstractIn this study, we showed the occurrence of phosphatidyl-L-threonine (PThr), phosphatidyl-L-aspartate (PAsp), and phosphatidyl-L-glutamate (PGlu) in rat brain. Analyses using an HPLC-ESI-MS and an amino acid analyzer showed the presence of L-threonine, L-aspartate, and L-glutamate in the acid-hydrolysates of phospholipids from porcine cerebrum, rat cerebrum, and rat liver. Results of ESI-MS/MS analyses with neutral loss scanning and product ion scanning suggest the presence of PThr-(18:0, 18:1), PThr-(18:0, 22:6), PAsp-(18:0, 18:1), PAsp-(18:0, 22:6), PGlu-(18:0, 18:1), and PGlu-(18:0, 22:6) in rat brain. This is the first study to identify 2 novel phospholipids, PAsp and PGlu, with a carboxylate-phosphate anhydride bond, in living organisms.en
dc.format.mimetypeapplication/pdf-
dc.language.isoeng-
dc.publisherElsevier B.V.en
dc.rights© 2011 Elsevier B.V.en
dc.rightsThis is not the published version. Please cite only the published version.en
dc.rightsこの論文は出版社版でありません。引用の際には出版社版をご確認ご利用ください。ja
dc.subjectAspartateen
dc.subjectGlutamateen
dc.subjectThreonineen
dc.subjectPhospholipidsen
dc.subjectMammalen
dc.subjectCarboxylate–phosphate anhydrideen
dc.titleIdentification of novel mammalian phospholipids containing threonine, aspartate, and glutamate as the base moiety.en
dc.typejournal article-
dc.type.niitypeJournal Article-
dc.identifier.ncidAA11644805-
dc.identifier.jtitleJournal of chromatography. B, Analytical technologies in the biomedical and life sciencesen
dc.identifier.volume879-
dc.identifier.issue29-
dc.identifier.spage3296-
dc.identifier.epage3302-
dc.relation.doi10.1016/j.jchromb.2011.04.033-
dc.textversionauthor-
dc.identifier.pmid21601537-
dcterms.accessRightsopen access-
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