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dc.contributor.author岡根谷, 利一ja
dc.contributor.author西澤, 秀治ja
dc.contributor.author飯島, 和芳ja
dc.contributor.author山岸, 貴裕ja
dc.contributor.author上垣内, 崇行ja
dc.contributor.author橋田, 巌ja
dc.contributor.author保坂, 典子ja
dc.contributor.alternativeOkaneya, Toshikazuen
dc.contributor.alternativeNishizawa, Shujien
dc.contributor.alternativeIijima, Kazuyoshien
dc.contributor.alternativeYamagishi, Takahiroen
dc.contributor.alternativeKamigaito, Takayukien
dc.contributor.alternativeHashida, Iwaoen
dc.contributor.alternativeHosaka, Norikoen
dc.date.accessioned2012-06-11T00:23:14Z-
dc.date.available2012-06-11T00:23:14Z-
dc.date.issued2012-04-
dc.identifier.issn0018-1994-
dc.identifier.urihttp://hdl.handle.net/2433/156301-
dc.description.abstractA total of 320 localized prostate cancer patients including 272 at low-risk and 48 at intermediate-risk were treated with permanent iodine-125 seed implants. Changes of lower urinary tract symptoms after the treatment were analyzed for one consecutive year using international prostate symptom score, quality of life (QOL) score and uroflowmetry. These patients did not have prostate hypertrophy or were not treated with any α1 blocker before the seed implant. Tamsulosin (0.2 mg/day) was prophylactically administered to all the patients for six months beginning the day after the seed implant. Both voiding and storage symptoms developed even in patients without any urinary symptoms before seed implant and worsened during the consecutive three months ; and, QOL also worsened after seed implant. Lower urinary tract symptoms continued to be significantly severe for six months compared with that before the seed implant, then improved gradually to almost the initial level after one year. It seems to take longer for storage symptoms to diminish to the initial level compared with voiding symptoms. Neoadjuvant hormone therapy improved neither voiding nor storage symptoms in patients without prostate hypertrophy less than 40 ml in volume. In conclusion, a more effective α1 blocker or other potent prophylactic drug therapy should be used on the patients after seed implant because the disadvantage of seed implant is probably only urinary disturbance.en
dc.format.mimetypeapplication/pdf-
dc.language.isojpn-
dc.publisher泌尿器科紀要刊行会ja
dc.rights許諾条件により本文は2013-05-01に公開ja
dc.subjectVoiding symptomen
dc.subjectStorage symptomen
dc.subjectProstate canceren
dc.subjectSeed implanten
dc.subjectIPSSen
dc.subject.ndc494.9-
dc.title前立腺癌に対する小線源治療後の下部尿路症状の解析ja
dc.title.alternativeClinical Evaluation of Lower Urinary Tract Symptoms Following Seed Implant for Prostate Canceren
dc.typedepartmental bulletin paper-
dc.type.niitypeDepartmental Bulletin Paper-
dc.identifier.ncidAN00208315-
dc.identifier.jtitle泌尿器科紀要ja
dc.identifier.volume58-
dc.identifier.issue4-
dc.identifier.spage185-
dc.identifier.epage191-
dc.textversionpublisher-
dc.sortkey01-
dc.address長野市民病院泌尿器科 ; 虎の門病院泌尿器科ja
dc.address長野市民病院泌尿器科ja
dc.address長野市民病院泌尿器科ja
dc.address長野市民病院泌尿器科ja
dc.address長野市民病院泌尿器科ja
dc.address長野市民病院放射線科ja
dc.address長野市民病院臨床病理科ja
dc.startdate.bitstreamsavailable2013-05-01-
dc.address.alternativeThe Department of Urology, Nagano Municipal Hospital ; The Department of Urology, Toranomon Hospitalen
dc.address.alternativeThe Department of Urology, Nagano Municipal Hospitalen
dc.address.alternativeThe Department of Urology, Nagano Municipal Hospitalen
dc.address.alternativeThe Department of Urology, Nagano Municipal Hospitalen
dc.address.alternativeThe Department of Urology, Nagano Municipal Hospitalen
dc.address.alternativeThe Department of Radiation Oncology, Nagano Municipal Hospitalen
dc.address.alternativeThe Department of Pathology, Nagano Municipal Hospitalen
dc.identifier.pmid22684258-
dcterms.accessRightsopen access-
dc.identifier.pissn0018-1994-
dc.identifier.jtitle-alternativeActa urologica Japonicala
dc.identifier.jtitle-alternativeHinyokika Kiyoen
Appears in Collections:Vol.58 No.4

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