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dc.contributor.authorMima, Takahiroen
dc.contributor.authorBaba, Shiroen
dc.contributor.authorYokoo, Noritakaen
dc.contributor.authorKaichi, Shinjien
dc.contributor.authorDoi, Takahiroen
dc.contributor.authorDoi, Hirakuen
dc.contributor.authorHeike, Toshioen
dc.contributor.alternative馬場, 志郎ja
dc.date.accessioned2012-10-05T06:39:47Z-
dc.date.available2012-10-05T06:39:47Z-
dc.date.issued2010-06-03-
dc.identifier.issn1749-8090-
dc.identifier.urihttp://hdl.handle.net/2433/159709-
dc.description.abstractCardiac resynchronization therapy (CRT) is a new treatment for refractory heart failure. However, most heart failure patients treated with CRT are middle-aged or old patients with idiopathic or ischemic dilated cardiomyopathy. We treated a 17 year 11 month old girl with dilated cardiomyopathy after mitral valve replacement (MVR) and septal anterior ventricular exclusion (SAVE). Seven years after the SAVE procedure, she presented complaining of palpitations and general fatigue with normal activity. Her echocardiogram showed reduced left ventricular function. Despite of optimal medical therapy, her left ventricular function continued to decline and she experienced regular arrhythmias such as premature ventricular contractions. We thus elected to perform cardiac resynchronization therapy with defibrillator (CRT-D). After CRT-D, her clinical symptoms improved dramatically and left ventricular ejection fraction (LVEF) improved from 31.2% to 51.3% as assessed by echocardiogram. Serum BNP levels decreased from 448.2 to 213.6 pg/ml. On ECG, arrhythmias were remarkably reduced and QRS duration was shortened from 174 to 152 msec. In conclusion, CRT-D is an effective therapeutic option for adolescent patients with refractory heart failure after left ventricular volume reduction surgery.en
dc.format.mimetypeapplication/pdf-
dc.language.isoeng-
dc.publisherBioMed Central Ltd.en
dc.rights© 2010 Mima et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.en
dc.subject.meshAdolescenten
dc.subject.meshArrhythmias, Cardiac/etiologyen
dc.subject.meshArrhythmias, Cardiac/surgeryen
dc.subject.meshCardiac Pacing, Artificialen
dc.subject.meshCardiac Surgical Procedures/adverse effectsen
dc.subject.meshCardiomyopathy, Dilated/etiologyen
dc.subject.meshCardiomyopathy, Dilated/therapyen
dc.subject.meshFemaleen
dc.subject.meshHeart Failure/etiologyen
dc.subject.meshHeart Failure/therapyen
dc.subject.meshHeart Valve Prosthesis Implantationen
dc.subject.meshHeart Ventricles/surgeryen
dc.subject.meshHumansen
dc.subject.meshMitral Valve/surgeryen
dc.subject.meshVentricular Dysfunction, Left/etiologyen
dc.subject.meshVentricular Dysfunction, Left/surgeryen
dc.titleEffective cardiac resynchronization therapy for an adolescent patient with dilated cardiomyopathy seven years after mitral valve replacement and septal anterior ventricular exclusion.en
dc.typejournal article-
dc.type.niitypeJournal Article-
dc.identifier.jtitleJournal of cardiothoracic surgeryen
dc.identifier.volume5-
dc.relation.doi10.1186/1749-8090-5-47-
dc.textversionpublisher-
dc.identifier.artnum47-
dc.identifier.pmid20525228-
dcterms.accessRightsopen access-
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