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タイトル: | Disseminated Nocardia farcinica infection in a patient with myasthenia gravis successfully treated by linezolid: a case report and literature review. |
著者: | Tanioka, Kosuke Nagao, Miki https://orcid.org/0000-0002-8886-6145 (unconfirmed) Yamamoto, Masaki Matsumura, Yasufumi https://orcid.org/0000-0001-8595-8944 (unconfirmed) Tabu, Hayato Matsushima, Aki Uemura, Kengo Matsumoto, Riki https://orcid.org/0000-0003-3985-9210 (unconfirmed) Ito, Yutaka Takakura, Shunji Takahashi, Ryosuke https://orcid.org/0000-0002-1407-9640 (unconfirmed) Ichiyama, Satoshi |
著者名の別形: | 長尾, 美紀 |
キーワード: | Invasive nocardiosis Linezolid Nocardia farcinica |
発行日: | Jun-2012 |
出版者: | Springer Japan |
誌名: | Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy |
巻: | 18 |
号: | 3 |
開始ページ: | 390 |
終了ページ: | 394 |
抄録: | Nocardiosis is increasingly being diagnosed because of a growing population of immunocompromised hosts and improvements in the detection of Nocardia species in clinical laboratories. Historically, sulphonamides have been the first-line therapy for the treatment of nocardiosis, but sulphonamides tend to have a high rate of drug allergy in clinical settings. In this report, we described a disseminated Nocardia farcinica infection that occurred in a patient with myasthenia gravis who suffered from multiple drug allergies and was successfully treated using linezolid. We undertook a review of the literature of previously reported cases of nocardiosis treated with linezolid. To date, only 15 cases of nocardiosis treated with linezolid have been published. All cases exhibited long-term tolerance of linezolid, and 14 of 15 cases showed either an improvement in or complete clearance of the infection. According to the literature review, linezolid is an attractive alternative to trimethoprim-sulfamethoxazole for the treatment of disseminated nocardiosis, despite limited clinical evidence to support this claim. |
著作権等: | The final publication is available at www.springerlink.com This is not the published version. Please cite only the published version. この論文は出版社版でありません。引用の際には出版社版をご確認ご利用ください。 |
URI: | http://hdl.handle.net/2433/160126 |
DOI(出版社版): | 10.1007/s10156-011-0315-1 |
PubMed ID: | 21997125 |
出現コレクション: | 学術雑誌掲載論文等 |
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