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| ファイル | 記述 | サイズ | フォーマット | |
|---|---|---|---|---|
| clpt.2011.38.pdf | 1.41 MB | Adobe PDF | 見る/開く |
完全メタデータレコード
| DCフィールド | 値 | 言語 |
|---|---|---|
| dc.contributor.author | Inoue, H | en |
| dc.contributor.author | Yamanaka, S | en |
| dc.contributor.alternative | 井上, 治久 | ja |
| dc.contributor.alternative | 山中, 伸弥 | ja |
| dc.date.accessioned | 2012-10-17T07:11:30Z | - |
| dc.date.available | 2012-10-17T07:11:30Z | - |
| dc.date.issued | 2011-05 | - |
| dc.identifier.issn | 0009-9236 | - |
| dc.identifier.uri | http://hdl.handle.net/2433/160140 | - |
| dc.description.abstract | Induced pluripotent stem cell (iPSC) technology is revolutionizing medical science, allowing the exploration of disease mechanisms and novel therapeutic molecular targets, and offering opportunities for drug discovery and proof-of-concept studies in drug development. This review focuses on the recent advancements in iPSC technology including disease modeling and control setting in its analytical paradigm. We describe how iPSC technology is integrated into existing paradigms of drug development and discuss the potential of iPSC technology in personalized medicine. | en |
| dc.format.mimetype | application/pdf | - |
| dc.language.iso | eng | - |
| dc.publisher | Nature Publishing Group | en |
| dc.rights | © 2012 American Society for Clinical Pharmacology and Therapeutics | en |
| dc.rights | This is not the published version. Please cite only the published version. | en |
| dc.rights | この論文は出版社版でありません。引用の際には出版社版をご確認ご利用ください。 | ja |
| dc.subject | iPS cell | en |
| dc.subject | drug development | en |
| dc.subject | disease modeling | en |
| dc.subject | control definition | en |
| dc.subject | animal model | en |
| dc.subject | personalized medicine | en |
| dc.subject.mesh | Animals | en |
| dc.subject.mesh | Cell Differentiation/physiology | en |
| dc.subject.mesh | Drug Discovery/methods | en |
| dc.subject.mesh | Drug Discovery/trends | en |
| dc.subject.mesh | Drug Evaluation, Preclinical/methods | en |
| dc.subject.mesh | Drug Evaluation, Preclinical/trends | en |
| dc.subject.mesh | Humans | en |
| dc.subject.mesh | Induced Pluripotent Stem Cells/cytology | en |
| dc.subject.mesh | Induced Pluripotent Stem Cells/transplantation | en |
| dc.subject.mesh | Nuclear Reprogramming/physiology | en |
| dc.title | The use of induced pluripotent stem cells in drug development. | en |
| dc.type | journal article | - |
| dc.type.niitype | Journal Article | - |
| dc.identifier.ncid | AA00607986 | - |
| dc.identifier.jtitle | Clinical pharmacology and therapeutics | en |
| dc.identifier.volume | 89 | - |
| dc.identifier.issue | 5 | - |
| dc.identifier.spage | 655 | - |
| dc.identifier.epage | 661 | - |
| dc.relation.doi | 10.1038/clpt.2011.38 | - |
| dc.textversion | author | - |
| dc.identifier.pmid | 21430656 | - |
| dcterms.accessRights | open access | - |
| 出現コレクション: | 学術雑誌掲載論文等 | |
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