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タイトル: | Pre- and perioperative factors affecting infection after living donor liver transplantation. |
著者: | Kaido, Toshimi Mori, Akira Ogura, Yasuhiro Ogawa, Kouhei Hata, Koichiro https://orcid.org/0000-0002-3609-6396 (unconfirmed) Yoshizawa, Atsushi Yagi, Shintaro https://orcid.org/0000-0001-7465-5761 (unconfirmed) Uemoto, Shinji |
著者名の別形: | 海道, 利実 |
キーワード: | Liver transplantation Infection Nutrition Body cell mass Branched-chain amino acids |
発行日: | Nov-2012 |
出版者: | Elsevier Inc. |
誌名: | Nutrition |
巻: | 28 |
号: | 11-12 |
開始ページ: | 1104 |
終了ページ: | 1108 |
抄録: | [Objective]: Infectious complications, including sepsis, that often occur after liver transplantation (LT) comprise the most frequent causes of in-hospital death. This study investigated the predictors of post-transplantation infectious complications to establish a strategy with which to improve short-term outcomes after LT. [Methods]: We used univariate and multivariate analyses to assess pre- and perioperative risk factors for post-transplantation infectious complications in 100 consecutive patients who underwent living donor LT from February 2008 through February 2010 at our institute. [Results]: Multivariate analysis showed that low preoperative body cell mass and the absence of preoperative supplementation with branched-chain amino acids were of prognostic significance for post-transplantation sepsis. In addition, Child–Pugh classification C and massive operative blood loss were independent risk factors for post-transplantation bacteremia, and preoperative low body cell mass was an independent risk factor for in-hospital death from infection. [Conclusion]: Pretransplantation nutritional intervention and decreases in operative blood loss would help prevent post-transplantation infectious complications from developing during living donor LT. Branched-chain amino acid supplementation before LT affects the occurrence of infectious complications. |
著作権等: | © 2012 Elsevier Inc. この論文は出版社版でありません。引用の際には出版社版をご確認ご利用ください。 This is not the published version. Please cite only the published version. |
URI: | http://hdl.handle.net/2433/160282 |
DOI(出版社版): | 10.1016/j.nut.2012.02.007 |
PubMed ID: | 23044161 |
出現コレクション: | 学術雑誌掲載論文等 |
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