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Title: Comparison of Long-Term Outcome After Percutaneous Coronary Intervention Versus Coronary Artery Bypass Grafting in Patients With Unprotected Left Main Coronary Artery Disease (from the CREDO-Kyoto PCI/CABG Registry Cohort-2).
Authors: Shiomi, Hiroki  kyouindb  KAKEN_id
Morimoto, Takeshi
Hayano, Mamoru
Furukawa, Yutaka
Nakagawa, Yoshihisa
Tazaki, Junichi  kyouindb  KAKEN_id
Imai, Masao  kyouindb  KAKEN_id
Yamaji, Kyohei
Tada, Tomohisa
Natsuaki, Masahiro
Saijo, Sayaka
Funakoshi, Shunsuke
Nagao, Kazuya
Hanazawa, Koji
Ehara, Natsuhiko
Kadota, Kazushige
Iwabuchi, Masashi
Shizuta, Satoshi  kyouindb  KAKEN_id
Abe, Mitsuru
Sakata, Ryuzo  KAKEN_id
Okabayashi, Hitoshi
Hanyu, Michiya
Yamazaki, Fumio
Shimamoto, Mitsuomi
Nishiwaki, Noboru
Imoto, Yutaka
Komiya, Tatsuhiko
Horie, Minoru
Fujiwara, Hisayoshi
Mitsudo, Kazuaki
Nobuyoshi, Masakiyo
Kita, Toru
Kimura, Takeshi  kyouindb  KAKEN_id
CREDO-Kyoto PCI/CABG Registry Cohort-2 Investigators
Author's alias: 木村,  剛
Issue Date: 1-Oct-2012
Publisher: Elsevier Inc.
Journal title: The American journal of cardiology
Volume: 110
Issue: 7
Start page: 924
End page: 932
Abstract: The long-term outcome of percutaneous coronary intervention (PCI) compared to coronary artery bypass grafting (CABG) for unprotected left main coronary artery disease (ULMCAD) remains to be investigated. We identified 1, 005 patients with ULMCAD of 15, 939 patients with first coronary revascularization enrolled in the CREDO-Kyoto PCI/CABG Registry Cohort-2. Cumulative 3-year incidence of a composite of death/myocardial infarction (MI)/stroke was significantly higher in the PCI group than in the CABG group (22.7% vs 14.8%, p = 0.0006, log-rank test). However, the adjusted outcome was not different between the PCI and CABG groups (hazard ratio [HR] 1.30, 95% confidence interval [CI] 0.79 to 2.15, p = 0.30). Stratified analysis using the SYNTAX score demonstrated that risk for a composite of death/MI/stroke was not different between the 2 treatment groups in patients with low (<23) and intermediate (23 to 33) SYNTAX scores (adjusted HR 1.70, 95% CI 0.77 to 3.76, p = 0.19; adjusted HR 0.86, 95% CI 0.37 to 1.99, p = 0.72, respectively), whereas in patients with a high SYNTAX score (≥33), it was significantly higher after PCI than after CABG (adjusted HR 2.61, 95% CI 1.32 to 5.16, p = 0.006). In conclusion, risk of PCI for serious adverse events seemed to be comparable to that after CABG in patients with ULMCAD with a low or intermediate SYNTAX score, whereas PCI compared with CABG was associated with a higher risk for serious adverse events in patients with a high SYNTAX score.
Rights: © 2012 Elsevier Inc.
この論文は出版社版でありません。引用の際には出版社版をご確認ご利用ください。This is not the published version. Please cite only the published version.
URI: http://hdl.handle.net/2433/160400
DOI(Published Version): 10.1016/j.amjcard.2012.05.022
PubMed ID: 22721575
Appears in Collections:Journal Articles

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