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Title: DNA as a chiral scaffold for asymmetric synthesis.
Authors: Park, Soyoung  kyouindb  KAKEN_id
Sugiyama, Hiroshi  kyouindb  KAKEN_id
Author's alias: 朴, 昭映
杉山, 弘
Keywords: DNA
asymmetric synthesis
helical chirality
hybrid catalyst
Issue Date: 31-Oct-2012
Publisher: MDPI
Journal title: Molecules
Volume: 17
Issue: 11
Start page: 12792
End page: 12803
Abstract: The application of DNA-based hybrid catalysts for enantioselective synthesis has recently emerged. These catalysts, self-assembled from DNA and a metal complex with a specific ligand through supramolecular or covalent anchoring strategies, have demonstrated high enantioselectivity in a variety of carbon-carbon or carbon-heteroatom bond-forming reactions and have expanded their role in asymmetric catalysis. In this review, we summarize the advent and significant progress of DNA-based asymmetric catalysis and discuss remaining challenges in using DNA as a chiral scaffold. We hope that this review will inspire many of today’s active scientists in asymmetric catalysis.
Rights: © 2012 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
URI: http://hdl.handle.net/2433/166079
DOI(Published Version): 10.3390/molecules171112792
PubMed ID: 23114615
Appears in Collections:Journal Articles

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