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DCフィールド | 値 | 言語 |
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dc.contributor.author | UENO, Sayo | en |
dc.contributor.author | YANAGITA, Ryo C. | en |
dc.contributor.author | MURAKAMI, Kazuma | en |
dc.contributor.author | MURAKAMI, Akira | en |
dc.contributor.author | TOKUDA, Harukuni | en |
dc.contributor.author | SUZUKI, Nobutaka | en |
dc.contributor.author | FUJIWARA, Takeshi | en |
dc.contributor.author | IRIE, Kazuhiro | en |
dc.contributor.alternative | 入江, 一浩 | ja |
dc.date.accessioned | 2013-08-02T05:04:25Z | - |
dc.date.available | 2013-08-02T05:04:25Z | - |
dc.date.issued | 2012-05 | - |
dc.identifier.issn | 0916-8451 | - |
dc.identifier.uri | http://hdl.handle.net/2433/176984 | - |
dc.description.abstract | Six bryostatins were isolated from Japanese bryozoan by evaluating their binding to the C1B domain of protein kinase Cδ (PKCδ). Structure-activity studies of bryostatins 4, 10, and 14 suggested that the ester group at C20 was not necessary for binding to and activating PKCδ. These bryostatins showed significant anti-tumor-promoting activity in induction tests with the Epstein-Barr virus early antigen. | en |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | - |
dc.publisher | Japan Society for Bioscience, Biotechnology, and Agrochemistry | en |
dc.rights | © 2012 by Japan Society for Bioscience, Biotechnology, and Agrochemistry | en |
dc.subject | protein kinase C | en |
dc.subject | bryostatin | en |
dc.subject | Bugula neritina | en |
dc.subject | tumor promotion | en |
dc.subject | Epstein-Barr virus | en |
dc.title | Identification and Biological Activities of Bryostatins from Japanese Bryozoan | en |
dc.type | journal article | - |
dc.type.niitype | Journal Article | - |
dc.identifier.ncid | AA10824164 | - |
dc.identifier.jtitle | Bioscience, Biotechnology, and Biochemistry | en |
dc.identifier.volume | 76 | - |
dc.identifier.issue | 5 | - |
dc.identifier.spage | 1041 | - |
dc.identifier.epage | 1043 | - |
dc.relation.doi | 10.1271/bbb.120026 | - |
dc.textversion | publisher | - |
dc.identifier.pmid | 22738985 | - |
dc.relation.url | https://www.jstage.jst.go.jp/article/bbb/76/5/76_120026/_article | - |
dcterms.accessRights | open access | - |
出現コレクション: | 学術雑誌掲載論文等 |
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