ダウンロード数: 1744
このアイテムのファイル:
ファイル | 記述 | サイズ | フォーマット | |
---|---|---|---|---|
59_411.pdf | 952.25 kB | Adobe PDF | 見る/開く |
完全メタデータレコード
DCフィールド | 値 | 言語 |
---|---|---|
dc.contributor.author | 小林, 将行 | ja |
dc.contributor.author | 斎藤, 允孝 | ja |
dc.contributor.author | 小丸, 淳 | ja |
dc.contributor.author | 深沢, 賢 | ja |
dc.contributor.author | 巣山, 貴仁 | ja |
dc.contributor.author | 赤倉, 功一郎 | ja |
dc.contributor.author | 市川, 智彦 | ja |
dc.contributor.author | 植田, 健 | ja |
dc.contributor.alternative | Kobayashi, Masayuki | en |
dc.contributor.alternative | Saito, Yoshitaka | en |
dc.contributor.alternative | Komaru, Atsushi | en |
dc.contributor.alternative | Fukasawa, Satoshi | en |
dc.contributor.alternative | Suyama, Takahito | en |
dc.contributor.alternative | Akakura, Koichiro | en |
dc.contributor.alternative | Ichikawa, Tomohiko | en |
dc.contributor.alternative | Ueda, Takeshi | en |
dc.date.accessioned | 2013-08-15T01:51:36Z | - |
dc.date.available | 2013-08-15T01:51:36Z | - |
dc.date.issued | 2013-07 | - |
dc.identifier.issn | 0018-1994 | - |
dc.identifier.uri | http://hdl.handle.net/2433/177508 | - |
dc.description.abstract | We examined the effect of neoadjuvant hormonal therapy (NHT) on biochemical failure. We retrospectively analyzed 146 high-risk prostate cancer patients (clinically (c), T1c-3N0M0) who underwent radical prostatectomy between June 2002 and March 2008. Thirty-eight patients were treated with NHT for ≥2 months (NHT group), and 108, with surgery alone (SA group). The study population comprised 89 cT1c-2N0M0 patients and 57 cT3N0M0 patients, and pathologically (p), 66 pT0-2N0M0 patients and 76 pT3N0M0 patients. Downstaging was noted in 36.4 and 0% of cT1c-2N0M0 patients and in 74.1 and 20.0% of cT3N0M0 patients in the NHT and SA groups, respectively. For both cT1c-2N0M0 and cT3N0M0 patients, the downstaging rate was significantly higher in the NHT group than in the SA group (p<0.01). Positive resection margin rates were significantly lower in the NHT group (34.2%) than in the SA group (65.7%) (p<0.01). The overall prostate-specific antigen (PSA) progression-free rate did not differ significantly between the 2 groups in both pT0-2N0M0 and pT3N0M0 patients. However, in pT0-2N0M0 patients with negative resection margins, the 5-year PSA progression-free rate was significantly lower in the NHT group than in the SA group (p<0.01), whereas this rate did not differ significantly between the groups in both pT0-2N0M0 and pT3N0M0 patients with positive resection margins. Although NHT seemed to have some effect on downstaging, its pathological effects could be underestimated. Thus, NHT was considered to have no significant effect on biochemical failure. | en |
dc.format.mimetype | application/pdf | - |
dc.language.iso | jpn | - |
dc.publisher | 泌尿器科紀要刊行会 | ja |
dc.rights | 許諾条件により本文は2014-08-01に公開 | ja |
dc.subject | Prostate cancer | en |
dc.subject | Neoadjuvant hormonal therapy | en |
dc.subject | Radical prostatectomy | en |
dc.subject.ndc | 494.9 | - |
dc.title | ハイリスク前立腺癌に対する根治的前立腺全摘除術における術前内分泌療法群と手術単独群の比較検討 | ja |
dc.type | departmental bulletin paper | - |
dc.type.niitype | Departmental Bulletin Paper | - |
dc.identifier.ncid | AN00208315 | - |
dc.identifier.jtitle | 泌尿器科紀要 | ja |
dc.identifier.volume | 59 | - |
dc.identifier.issue | 7 | - |
dc.identifier.spage | 411 | - |
dc.identifier.epage | 418 | - |
dc.textversion | publisher | - |
dc.sortkey | 02 | - |
dc.address | 千葉県がんセンター前立腺センター泌尿器科 | ja |
dc.address | 千葉県がんセンター前立腺センター泌尿器科 | ja |
dc.address | 千葉県がんセンター前立腺センター泌尿器科 | ja |
dc.address | 千葉県がんセンター前立腺センター泌尿器科 | ja |
dc.address | 東京厚生年金病院泌尿器科 | ja |
dc.address | 千葉大学大学院医学研究院泌尿器科 | ja |
dc.address | 東京厚生年金病院泌尿器科 | ja |
dc.address | 千葉県がんセンター前立腺センター泌尿器科 | ja |
dc.startdate.bitstreamsavailable | 2014-08-01 | - |
dc.address.alternative | The Prostate Center and Division of Urology, Chiba Cancer Center | en |
dc.address.alternative | The Prostate Center and Division of Urology, Chiba Cancer Center | en |
dc.address.alternative | The Prostate Center and Division of Urology, Chiba Cancer Center | en |
dc.address.alternative | The Prostate Center and Division of Urology, Chiba Cancer Center | en |
dc.address.alternative | The Department of Urology, Tokyo Kosei Nenkin Hospital | en |
dc.address.alternative | The Department of Urology, Graduate School of Medicine, Chiba University | en |
dc.address.alternative | The Department of Urology, Tokyo Kosei Nenkin Hospital | en |
dc.address.alternative | The Prostate Center and Division of Urology, Chiba Cancer Center | en |
dc.identifier.pmid | 23945319 | - |
dcterms.accessRights | open access | - |
dcterms.alternative | Neoadjuvant Hormonal Therapy Versus Surgery Alone for Radical Prostatectomy in High-Risk Prostate Cancer Patients | ja |
dc.identifier.pissn | 0018-1994 | - |
dc.identifier.jtitle-alternative | Acta urologica Japonica | la |
dc.identifier.jtitle-alternative | Hinyokika Kiyo | en |
出現コレクション: | Vol.59 No.7 |
このリポジトリに保管されているアイテムはすべて著作権により保護されています。