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ファイル | 記述 | サイズ | フォーマット | |
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B978-0-12-407695-2.00008-1.pdf | 1.52 MB | Adobe PDF | 見る/開く |
タイトル: | Transcription factors in alkaloid biosynthesis. |
著者: | Yamada, Yasuyuki Sato, Fumihiko ![]() |
著者名の別形: | 佐藤, 文彦 |
キーワード: | Alkaloid biosynthesis Transcription factor Jasmonate signaling Transcriptional regulation Secondary metabolism |
発行日: | 2013 |
出版者: | Elsevier Inc. |
誌名: | International review of cell and molecular biology |
巻: | 305 |
開始ページ: | 339 |
終了ページ: | 382 |
抄録: | Higher plants produce a large variety of low-molecular weight secondary compounds. Among them, nitrogen-containing alkaloids are the most biologically active and are often used pharmaceutically. Whereas alkaloid chemistry has been intensively investigated, alkaloid biosynthesis, including the relevant biosynthetic enzymes, genes and their regulation, and especially transcription factors, is largely unknown, as only a limited number of plant species produce certain types of alkaloids and they are difficult to study. Recently, however, several groups have succeeded in isolating the transcription factors that are involved in the biosynthesis of several types of alkaloids, including bHLH, ERF, and WRKY. Most of them show Jasmonate (JA) responsiveness, which suggests that the JA signaling cascade plays an important role in alkaloid biosynthesis. Here, we summarize the types and functions of transcription factors that have been isolated in alkaloid biosynthesis, and characterize their similarities and differences compared to those in other secondary metabolite pathways, such as phenylpropanoid and terpenoid biosyntheses. The evolution of this biosynthetic pathway and regulatory network, as well as the application of these transcription factors to metabolic engineering, is discussed. |
著作権等: | © 2013 Elsevier Inc. この論文は出版社版でありません。引用の際には出版社版をご確認ご利用ください。 This is not the published version. Please cite only the published version. |
URI: | http://hdl.handle.net/2433/178034 |
DOI(出版社版): | 10.1016/B978-0-12-407695-2.00008-1 |
PubMed ID: | 23890386 |
出現コレクション: | 学術雑誌掲載論文等 |
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