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Title: Focal choroidal excavation in eyes with central serous chorioretinopathy.
Authors: Ellabban, Abdallah A
Tsujikawa, Akitaka  kyouindb  KAKEN_id
Ooto, Sotaro  kyouindb  KAKEN_id
Yamashiro, Kenji  KAKEN_id
Oishi, Akio  kyouindb  KAKEN_id  orcid (unconfirmed)
Nakata, Isao
Miyake, Masahiro  kyouindb  KAKEN_id
Akagi-Kurashige, Yumiko
Ueda-Arakawa, Naoko
Arichika, Shigeta
Yoshitake, Shin
Takahashi, Ayako  kyouindb  KAKEN_id
Yoshimura, Nagahisa  KAKEN_id
Author's alias: 辻川, 明孝
Issue Date: Oct-2013
Publisher: Elsevier Inc.
Journal title: American journal of ophthalmology
Volume: 156
Issue: 4
Start page: 673
End page: 683.e1
Abstract: [Purpose]To study the prevalence and 3-dimensional (3-D) tomographic features of focal choroidal excavations in eyes with central serous chorioretinopathy (CSC) using swept-source optical coherence tomography (OCT). [Design]Prospective, cross-sectional study. [Methods]We examined 116 consecutive eyes with CSC with a prototype 3-D swept-source OCT. 3-D images of the shape of the macular area, covering 6 × 6 mm2, were reconstructed by segmentation of the outer surface of the retinal pigment epithelium (RPE). [Results]The 3-D swept-source OCT detected focal choroidal excavations in 9 eyes (7.8%). The 3-D scanning protocol, coupled with en face scans, allowed for clear visualization of the excavation morphology. In 5 eyes with focal excavations, unusual choroidal tissue was found beneath the excavation, bridging the bottom of the excavation and the outer choroidal boundary. Additionally, 3 of those 5 eyes showed a suprachoroidal space below the excavation, as if the outer choroidal boundary is pulled inward by this bridging tissue. The focal choroidal excavations were located within fluorescein leakage points and areas of choroidal hyperpermeability. Eyes with focal choroidal excavations were more myopic (−4.42 ± 2.92 diopters) than eyes without excavations (−0.27 ± 1.80 diopters, P = .001). Subfoveal choroidal thickness was significantly thinner (301.3 ± 60.1 μm) in eyes with focal excavations than in eyes without the excavations (376.6 ± 104.8 μm, P = .036). [Conclusions]Focal choroidal excavations were present in 7.8% of eyes with CSC. In these eyes, focal choroidal excavations may have formed from RPE retraction caused by focal scarring of choroidal connective tissue.
Rights: © 2013 Elsevier Inc.
この論文は出版社版でありません。引用の際には出版社版をご確認ご利用ください。This is not the published version. Please cite only the published version.
DOI(Published Version): 10.1016/j.ajo.2013.05.010
PubMed ID: 23831223
Appears in Collections:Journal Articles

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