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j.bbrc.2013.09.118.pdf | 430.61 kB | Adobe PDF | 見る/開く |
タイトル: | Different phosphorylation rates among vertebrate cone visual pigments with different spectral sensitivities. |
著者: | Tsutsui, Kei Tachibanaki, Shuji Shimauchi-Matsukawa, Yoshie Shichida, Yoshinori Kawamura, Satoru |
著者名の別形: | 筒井, 圭 |
キーワード: | Cone visual pigment Phosphorylation GRK |
発行日: | 1-Nov-2013 |
出版者: | Elsevier Inc. |
誌名: | Biochemical and biophysical research communications |
巻: | 440 |
号: | 4 |
開始ページ: | 630 |
終了ページ: | 634 |
抄録: | Cone photoreceptor subtypes having different spectral sensitivities exhibit different recovery kinetics in their photoresponses in some vertebrates. Phosphorylation by G protein-coupled receptor kinase (GRK) is essential for the rapid inactivation of light-activated visual pigment, which is the rate-limiting step of the cone photoresponse recovery in salamander. In this study we compared the rate of light-dependent phosphorylation by GRK7 of carp green- and blue-sensitive cone visual pigments. Blue pigment was phosphorylated significantly less effectively than green pigment, suggesting that the difference in the pigment phosphorylation rate is responsible for the difference in photoresponse kinetics among cone photoreceptor subtypes. |
著作権等: | © 2013 Elsevier Inc. この論文は著者最終稿です。内容が印刷版と異なることがありますので、引用の際には出版社版をご確認ご利用ください。This is the Accepted Author Manuscript. Please cite only the published version. |
URI: | http://hdl.handle.net/2433/179767 |
DOI(出版社版): | 10.1016/j.bbrc.2013.09.118 |
PubMed ID: | 24113380 |
出現コレクション: | 学術雑誌掲載論文等 |
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