このアイテムのアクセス数: 247

このアイテムのファイル:
ファイル 記述 サイズフォーマット 
bpb.b13-00491.pdf860.4 kBAdobe PDF見る/開く
タイトル: Inhalation of the Essential Oil of Piper guineense from Cameroon Shows Sedative and Anxiolytic-Like Effects in Mice
著者: Tankam, Joan Manjuh
Ito, Michiho  kyouindb  KAKEN_id
著者名の別形: 伊藤, 美千穂
キーワード: Piper guineense
inhalation
sedative
linalool
3,5-dimethoxytoluene
発行日: Oct-2013
出版者: Pharmaceutical Society of Japan
誌名: Biological and Pharmaceutical Bulletin
巻: 36
号: 10
開始ページ: 1608
終了ページ: 1614
抄録: The aromatherapeutical potential of Piper guineense essential oil was investigated in mice via inhalation administration, and the active compounds were identified. An open field test and light/dark transition test were used to evaluate the sedative and anxiolytic activities of this essential oil, respectively. P. guineense essential oil showed significant sedative activity at an effective dose of 4.0×10[−5] mg per cage compared to the control group. It also showed potent anxiolytic effect at a dose of 4.0×10[−6] mg per cage. The main compounds of P. guineense essential oil were linalool (41.8%) and 3,5-dimethoxytoluene (10.9%). These two main compounds were shown to play a major role in the sedative activity of P. guineense essential oil. These results suggest that inhalation of P. guineense essential oil might induce a mild tranquilizing effect.
著作権等: © 2013 The Pharmaceutical Society of Japan
URI: http://hdl.handle.net/2433/180077
DOI(出版社版): 10.1248/bpb.b13-00491
出現コレクション:学術雑誌掲載論文等

アイテムの詳細レコードを表示する

Export to RefWorks


出力フォーマット 


このリポジトリに保管されているアイテムはすべて著作権により保護されています。