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DCフィールド | 値 | 言語 |
---|---|---|
dc.contributor.author | 増田, 光伸 | ja |
dc.contributor.author | 村井, 哲夫 | ja |
dc.contributor.author | 長田, 裕 | ja |
dc.contributor.author | 河合, 正記 | ja |
dc.contributor.author | 春日, 純 | ja |
dc.contributor.author | 横溝, 由美子 | ja |
dc.contributor.author | 黒田, 普之介 | ja |
dc.contributor.author | 中村, 麻美 | ja |
dc.contributor.author | 野口, 剛 | ja |
dc.contributor.alternative | Masuda, Mitsunobu | en |
dc.contributor.alternative | Murai, Tetsuo | en |
dc.contributor.alternative | Osada, Yutaka | en |
dc.contributor.alternative | Kawai, Masaki | en |
dc.contributor.alternative | Kasuga, Jun | en |
dc.contributor.alternative | Yokomizo, Yumiko | en |
dc.contributor.alternative | Kuroda, Shinnosuke | en |
dc.contributor.alternative | Nakamura, Mami | en |
dc.contributor.alternative | Noguchi, Go | en |
dc.date.accessioned | 2014-04-23T23:55:12Z | - |
dc.date.available | 2014-04-23T23:55:12Z | - |
dc.date.issued | 2014-02 | - |
dc.identifier.issn | 0018-1994 | - |
dc.identifier.uri | http://hdl.handle.net/2433/185876 | - |
dc.description.abstract | We performed additional administration of dutasteride in patients who did not respond sufficiently to α1-adrenoceptor antagonist treatment for lower urinary tract symptoms (LUTS) associated with benign prostatic hyperplasia (BPH) (LUTS/BPH). Among 76 registered patients, efficacy was analyzed in 58 patients. International Prostate Symptom Score (IPSS), subscores for voiding and storage symptoms and quality of life (QOL) on the IPSS, and Overactive Bladder Symptom Score (OABSS) were all significantly improved from the third month of administration compared to the time of initiating additional administration of dutasteride. Additional administration of dutasteride also significantly reduced prostate volume, and residual urine with the exception of the sixth month after administration. Age at initiation of administration and voiding symptom subscore on the IPSS were clinical factors affecting the therapeutic effects of dutasteride. The rate of improvement with treatment decreased with increasing age at initiation of dutasteride administration, and increased as voiding symptom subscore on the IPSS increased. Therefore, additional administration of dutasteride appears useful for cases of LUTS/BPH in which a sufficient response is not achieved with α1-adrenoceptor antagonist treatment. Because patients who have severe voiding symptoms or begin dutasteride at an early age may be expected to respond particularly well to dutasteride in terms of clinical efficacy, they were considered to be suitable targets for additional administration. | en |
dc.format.mimetype | application/pdf | - |
dc.language.iso | jpn | - |
dc.publisher | 泌尿器科紀要刊行会 | ja |
dc.rights | 許諾条件により本文は2015-03-01に公開 | ja |
dc.subject | Benign prostatic hyperplasia | en |
dc.subject | Dutasteride | en |
dc.subject | 5 alpha-reductase inhibitor | en |
dc.subject | α1 -adrenoceptor antagonist | en |
dc.subject.ndc | 494.9 | - |
dc.title | α1 遮断薬にて効果が不十分であった前立腺肥大症患者に対するデュタステリドの追加投与 : デュタステリドの治療効果に影響を及ぼす臨床的因子の検討 | ja |
dc.title.alternative | Additional Administration of Dutasteride in Patients with Benign Prostatic Hyperplasia who Did Not Respond Sufficiently to α1-Adrenoceptor Antagonist : Investigation of Clinical Factors Affecting the Therapeutic Effect of Dutasteride | en |
dc.type | departmental bulletin paper | - |
dc.type.niitype | Departmental Bulletin Paper | - |
dc.identifier.ncid | AN00208315 | - |
dc.identifier.jtitle | 泌尿器科紀要 | ja |
dc.identifier.volume | 60 | - |
dc.identifier.issue | 2 | - |
dc.identifier.spage | 61 | - |
dc.identifier.epage | 67 | - |
dc.textversion | publisher | - |
dc.sortkey | 02 | - |
dc.address | 増田泌尿器科 | ja |
dc.address | 国際親善総合病院 | ja |
dc.address | 国際親善総合病院 | ja |
dc.address | 国際親善総合病院 | ja |
dc.address | 茅ケ崎市立病院 | ja |
dc.address | 横浜南共済病院 | ja |
dc.address | 国際親善総合病院 | ja |
dc.address | 国際親善総合病院 | ja |
dc.address | 国際親善総合病院 | ja |
dc.address.alternative | Masuda Urological Clinic | en |
dc.address.alternative | International Goodwill Hospital | en |
dc.address.alternative | International Goodwill Hospital | en |
dc.address.alternative | International Goodwill Hospital | en |
dc.address.alternative | Chigasaki City Hospital | en |
dc.address.alternative | Yokohama Minami Kyousai Hospital | en |
dc.address.alternative | International Goodwill Hospital | en |
dc.address.alternative | International Goodwill Hospital | en |
dc.address.alternative | International Goodwill Hospital | en |
dc.identifier.pmid | 24755815 | - |
dcterms.accessRights | open access | - |
datacite.date.available | 2015-03-01 | - |
dc.identifier.pissn | 0018-1994 | - |
dc.identifier.jtitle-alternative | Acta urologica Japonica | la |
dc.identifier.jtitle-alternative | Hinyokika Kiyo | en |
出現コレクション: | Vol. 60 No. 2 |
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