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タイトル: | Choriocarcinoma syndrome を来した性腺外胚細胞腫瘍に対してModified BEP レジメンによる導入化学療法が奏効した1例 |
その他のタイトル: | Modified BEP Regimen Leads to Abatement of Choriocarcinoma Syndrome in a Patient with Extra Gonadal Germ Cell Tumor : A Case Report |
著者: | 大島, 純平 植村, 元秀 加藤, 大悟 永原, 啓 木内, 寛 辻村, 晃 野々村, 祝夫 |
著者名の別形: | Oshima, Jumpei Uemura, Motohide Kato, Taigo Nagahara, Akira Kiuchi, Hiroshi Tsujimura, Akira Nonomura, Norio |
キーワード: | Choriocarcinoma syndrome Modified BEP |
発行日: | Apr-2014 |
出版者: | 泌尿器科紀要刊行会 |
誌名: | 泌尿器科紀要 |
巻: | 60 |
号: | 4 |
開始ページ: | 183 |
終了ページ: | 187 |
抄録: | We present a case study of a 46-year-old man with extra gonadal germ cell tumor with multiple lung metastases and very high levels (324, 100 mIU/ml) of the tumor marker human chorionic gonadotropin (hCG). He underwent chemotherapy with VP-16, ifosfamide and cisplatinum regimen, but on day 2, he noticed strong dyspnea. A chest X-ray showed bilateral infiltration of the lungs, and he was diagnosed with acute respiratory distress syndrome (ARDS) from choriocarcinoma syndrome. After ARDS improved, he underwent modified bleomycin, VP-16 and cisplatinum for induction therapy again. After salvage chemotherapies, levels of the tumor marker hCG decreased to normal levels, and retroperitoneal lymph node dissection and left lung wedge resection were performed to confirm pathological complete remission. No obvious recurrence, as shown by tumor markers and imaging studies, has been observed for 17 months after the treatments. |
著作権等: | 許諾条件により本文は2015/05/01に公開 |
URI: | http://hdl.handle.net/2433/187760 |
PubMed ID: | 24882231 |
出現コレクション: | Vol. 60 No. 4 |
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