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タイトル: | Chromosomal differentiation of schistosomes: what is the message? |
著者: | Hirai, Hirohisa |
著者名の別形: | 平井, 啓久 |
キーワード: | chiasma frequency constitutive heterochromatin telomere squence localization geographical distribution schistosomes |
発行日: | 8-Sep-2014 |
出版者: | Frontiers Media SA |
誌名: | Frontiers in Genetics |
巻: | 5 |
論文番号: | 301 |
抄録: | As the only group of flukes with dioecism, schistosomes are unique organisms; they not only have intriguing biological and evolutionary aspects but also are responsible for major public health problems in the developing world. Schistosomiasis caused by this fluke affects approximately 210 million people in 76 countries. In order to facilitate the discovery of eradication methods for this disease, fundamental biological outcomes must be made available. Whole genome sequence data represent one such resource applicable to discovering eradication methods and measures. Herein, I describe three remarkable chromosomal changes and briefly discuss the differentiation of the Asian and African groups of this parasite taxon. Chromosomal data and evolutionary aspects will enable us to exploit genomic information for advancing schistosome studies. |
著作権等: | © 2014 Hirai. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
URI: | http://hdl.handle.net/2433/189693 |
DOI(出版社版): | 10.3389/fgene.2014.00301 |
PubMed ID: | 25250045 |
出現コレクション: | 学術雑誌掲載論文等 |
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