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Title: 集学的治療にて比較的長期予後を得られている前立腺小細胞癌の1例
Other Titles: Small Cell Carcinoma of the Prostate Effectively Treated for Relatively Long Term : A Case Report
Authors: 堀江, 憲吾  KAKEN_name
亀山, 紘司  KAKEN_name
水谷, 晃輔  KAKEN_name
菅原, 崇  KAKEN_name
清家, 健作  KAKEN_name
土屋, 朋大  KAKEN_name
安田, 満  KAKEN_name
横井, 繁明  KAKEN_name
仲野, 正博  KAKEN_name
出口, 隆  KAKEN_name
酒々井, 夏子  KAKEN_name
広瀬, 善信  KAKEN_name
Author's alias: Horie, Kengo
Kameyama, Koji
Mizutani, Kosuke
Sugawara, Takashi
Seike, Kensaku
Tsuchiya, Tomohiro
Yasuda, Mitsuru
Yokoi, Shigeaki
Nakano, Masahiro
Deguchi, Takashi
Suzui, Natsuko
Hirose, Yoshinobu
Keywords: Prostatic small cell carcinoma
Issue Date: Oct-2014
Publisher: 泌尿器科紀要刊行会
Journal title: 泌尿器科紀要 = Acta urologica Japonica
Volume: 60
Issue: 10
Start page: 517
End page: 521
Abstract: A 72-year-old Japanese man was referred to a hospital because of urinary retention. Digital rectal examination revealed a stony, hard nodule in the prostate. A high level of serum PSA was not detected. Prostatic biopsy was performed, and pathological examination indicated adenocarcinoma of the prostate. He was referred to our hospital for treatment. Imaging examinations revealed no metastases (T4N0M0), so we re-evaluated the biopsy specimens. Immunohistochemical examination revealed prostatic small cell carcinoma. His levels of neuron-specific enolase (NSE) and pro-gastrin-releasing peptide (Pro-GRP) were high. We treated him with combination chemotherapy comprising irinotecan and cisplatin, and the treatment waseffective. After four coursesof the chemotherapy, levelsof NSE and Pro-GRP had decreased, and the prostatic mass had decreased in size. Needle rebiopsy of the prostate demonstrated no evidence of malignancy. Adjuvant external beam radiation therapy wasals o performed. The patient iss till alive at 18 month after diagnosis with no evidence of relapse or metastasis of the disease.
Rights: 許諾条件により本文は2015/11/01に公開
PubMed ID: 25391785
Appears in Collections:Vol. 60 No. 10

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