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タイトル: Effect of an intermediate-frequency magnetic field of 23 kHz at 2 mT on chemotaxis and phagocytosis in neutrophil-like differentiated human HL-60 cells.
著者: Koyama, Shin  kyouindb  KAKEN_id
Narita, Eijiro
Shinohara, Naoki  kyouindb  KAKEN_id
Miyakoshi, Junji  kyouindb  KAKEN_id
著者名の別形: 宮越, 順二
キーワード: induction-heating (IH) cooktop
intermediate-frequency (IF) magnetic field
neutrophil
chemotaxis
phagocytosis
発行日: Sep-2014
出版者: MDPI
誌名: International journal of environmental research and public health
巻: 11
号: 9
開始ページ: 9649
終了ページ: 9659
抄録: Public concerns about potential health risks of intermediate-frequency (IF) electromagnetic fields are increasing, especially as the use of induction-heating cooktops has spread extensively in Japan and Europe. In order to investigate the properties of IF electromagnetic fields, we examined the effect of exposure to a 23-kHz IF magnetic field of 2 mT for 2, 3, or 4 h on neutrophil chemotaxis and phagocytosis using differentiated human HL-60 cells. Compared with sham exposure, exposure to the IF magnetic field had no effect on neutrophil chemotaxis or phagocytosis. Previous studies demonstrated that exposure to a 23-kHz IF magnetic field of 2 mT (about 74-times the maximum value recommended by the International Commission for Nonionizing Radiation Protection guidelines) may affect the first-line immune responses in humans. To our knowledge, this is the first study to evaluate the effects of IF magnetic fields on cellular immune responses. We found that exposure to an IF magnetic field of 2 mT has minimal if any effect on either the chemotaxis or phagocytic activity of neutrophil-like human HL-60 cells.
著作権等: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
URI: http://hdl.handle.net/2433/191215
DOI(出版社版): 10.3390/ijerph110909649
PubMed ID: 25233011
出現コレクション:学術雑誌掲載論文等

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