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dc.contributor.authorFujita, Misaoja
dc.contributor.authorHayashi, Yoshinorija
dc.contributor.authorTashiro, Shimonja
dc.contributor.authorTakashima, Kyokoja
dc.contributor.authorNakazawa, Eisukeja
dc.contributor.authorAkabayashi, Akiraja
dc.contributor.alternative藤田, みさおja
dc.date.accessioned2014-11-21T04:20:55Z-
dc.date.available2014-11-21T04:20:55Z-
dc.date.issued2014-10-06-
dc.identifier.issn1478-4505ja
dc.identifier.urihttp://hdl.handle.net/2433/191224-
dc.description.abstract[Background]To establish appropriate measures that deal with incidental findings (IFs), the neuroscience community needs to address various ethical issues. The current state of research facilities regarding IFs and investigator attitudes as well as potentially eligible research participants must be assessed prior to future discussions and before the development of policies and guidelines. To this end, we conducted two questionnaire surveys to clarify i) how IFs are addressed at neuroimaging research facilities in Japan and ii) the views of investigators and potential research participants regarding the handling of IFs. [Methods]Thirty-one principal investigators (PIs) involved in the Strategic Research Program for Brain Sciences (SRPBS), a government-funded project, were asked to fill out a questionnaire regarding ways IFs were handled at the facility. A total of 110 investigators engaged in SRPBS tasks, including 31 PIs who participated in the research facility survey and researchers conducting studies under the management of the PIs, and 500 individuals from the general public (i.e., general population) were asked to select the most appropriate way to deal with IFs in two scenarios, namely the medical school and humanities and social sciences department scenarios. [Results]More than 40% of PIs responded that they did not know or were unsure of what type of approach was employed to handle IFs at their research facilities. Nevertheless, they were willing to improve the current status if sufficient resources were provided. With regard to specialist involvement, 37.7% of investigators responded that it was appropriate to have a specialist check all images in the medical school scenario, whereas 13.3% responded that such involvement was appropriate in the humanities and social sciences department scenario. In contrast, 76.1% and 61.0% of the general population indicated that specialist involvement was appropriate in the medical school and humanities and social sciences department scenarios, respectively. These results show that expectations of the general population exceed those of investigators regarding measures to address IFs. Both investigators and the general population demanded more responsibility from PIs at medical institutions, compared to PIs at non-medical institutions. [Conclusions]Based on our preliminary results, we recommended that a licensed physician perform a screening test to appropriately examine clear abnormalities. These recommendations were implemented by the SRPBS as guidelines for handling IFs in national research projects in Japan.ja
dc.format.mimetypeapplication/pdfja
dc.language.isoengja
dc.publisherBioMed Central Ltd.ja
dc.rights© 2014 Fujita et al.; licensee BioMed Central Ltd.ja
dc.rightsThis is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.-
dc.subjectGeneral populationja
dc.subjectIncidental findingsja
dc.subjectInvestigatorsja
dc.subjectJapanja
dc.subjectNeuroimagingja
dc.subjectQuestionnairesja
dc.titleHandling incidental findings in neuroimaging research in Japan: current state of research facilities and attitudes of investigators and the general population.ja
dc.type.niitypeJournal Articleja
dc.identifier.jtitleHealth research policy and systemsja
dc.identifier.volume12ja
dc.relation.doi10.1186/1478-4505-12-58ja
dc.textversionpublisherja
dc.identifier.artnum58ja
dc.identifier.pmid25287578-
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